Ultra High Performance Liquid Chromatograph (UHPLC)

Ultra high-performance liquid chromatography, UHPLC, uses columns packed with porous sub-2-µm particles (usually 1.8 µm) to vastly increase throughput and resolving power compared to conventional 5-µm columns. Pressures can surpass 19,000 psi. Limited solvent consumption, the ability to work under a broader pressure range, and lower band broadening are further enhancements. UHPLC’s 10× reduction in analysis time strengthens its popularity in areas including the pharmaceutical industry, food safety, and the clinical field. The choice of detectors for use with UHPLC is wide-ranging, including UV-VIS, fluorescence, photodiode array, ELSD, quadrupole, and most recently, refractive index. For flexibility, many instruments offer the ability to run both conventional and UHPLC on one instrument. A final tip: When making the switch from HPLC to UHPLC, resist the temptation to overload the smaller columns.

Discover and compare Ultra High Performance Liquid Chromatographs:

CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™ UltiMate™ 3000 Standard SD Dual SystemThermo Scientific™ UltiMate™ 3000 Basic Automated SystemThermo Scientific™ UltiMate™ 3000 Basic Manual SystemThermo Scientific™ Vanquish™ Horizon UHPLC SystemThermo Scientific™ Vanquish™ LC Systems
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Catalog NumberIQLAAAGABHFAPBMBFDIQLAAAGABHFAPBMBFCIQLAAAGABHFAPBMBFBIQLAAAGABHFAPUMZZZIQLAAAGABHFAPUMZZZ
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DescriptionThe Thermo Scientific ™ UltiMate™ 3000 Standard Dual System offers numerous options for improving the information yield of all analyses and can still be operated as a regular single-channel system. The dual system makes it easy to configure Online-SPE, Orthogonal, Parallel or Tandem separations, ... Read MoreThe Thermo Scientific™ UltiMate™ 3000 Automated system offers unique LC and entry level UHPLC capabilities without compromise. The integrated autosampler and thermostatted column compartment deliver retention time precision and the ability to fine tune backpressure, resolution and speed. With ... Read MoreThe Thermo Scientific™ UltiMate™ 3000 Basic Manual system offers unique LC and entry level UHPLC capabilities without compromising on quality and robustness.The Thermo Scientific™ Vanquish™ Horizon UHPLC System is built from the ground up to deliver better results with superior separations and easier interaction with no trade-offs in performance, robustness, or ease-of-use. This fully integrated and biocompatible system features high sample capacity for... Read MoreToday’s scientists deserve the best analytical tools available; tools that empower to achieve the next scientific breakthrough, measure the previously unmeasurable or deliver outstanding quality results dependably. The Vanquish systems improve performance and repeatability with no trade-offs in ... Read More
QuantityEAEAEAEAEA
Flow Rate10 mL/min10 mL/min10 mL/min8 mL/min8 mL/min
Max. Pressure62 Mpa / 620 bar / 9000 psi62 Mpa / 620 bar / 9000 psi62 Mpa / 620 bar / 9000 psiUp to 1500 bar (22,000 psi)up to 1000 bar (15,000psi)
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