A gel permeation chromatograph (GPC) is used to separate the components of a sample by size, this is known as size-exclusion chromatography (SEC).
GPC systems are widely used to analyze polymers and proteins in manufacturing, chemistry, and biology labs for quality control and analysis. GPC systems are composed of porous beads (the gel) inside a column, a pump to move the sample and eluent through the column, and a detector to detect when different analytes are eluted through the column. The detectors can be concentration sensitive or molecular weight sensitive.
Each gel permeation system has a range of sizes it can detect based on the pore sizes of the beads in the column, so before deciding on a system make sure you know the parameters you need. There are different types of porous beads that have varying affinities for materials and it is best for the gel to have a low affinity for the material you wish to analyze.
Discover and compare Gel Permeation Chromatography Systems:
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| Company | Malvern Panalytical |
| Item | OMNISEC GPC/SEC UHPLC/UPLC Multi-Detector System |
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| Catalog Number | OMNISEC |
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| Type | Gel Permeation Chromatography (GPC) / Size Exclusion Chromatography (SEC) |
| Detector(s) | Differential refractive index, Light scattering, Viscometer, Diode-array-based UV/Vis spectrometer |
| Flow Rate | 0.005 to 10 mL/min |
| Description | Meet the world’s most advanced multi-detector GPC/SEC system, OMNISEC. In OMNISEC, Malvern's expertise has enabled the development of the most sensitive and accurate UHPLC/UPLC multi-detector GPC/SEC system available for protein characterization and polymer characterisation, both synthetic and Meet the world’s most advanced multi-detector GPC/SEC system, OMNISEC. In OMNISEC, Malvern's expertise has enabled the development of the most sensitive and accurate UHPLC/UPLC multi-detector GPC/SEC system available for protein characterization and polymer characterisation, both synthetic and natural.
OMNISEC includes OMNISEC RESOLVE, the integrated GPC/SEC module, OMNISEC REVEAL, the integrated multi-detector module and OMNISEC software for the characterization of synthetic and natural polymers, and proteins.
OMNISEC RESOLVE combines an integrated pump, degasser, autosampler and column oven in a single advanced separations unit.
OMNISEC REVEAL is the most advanced integrated GPC/SEC multi-detector available, incorporating refractive index, UV/Vis absorbance, light scattering and intrinsic viscosity detectors.
Features:
- Optimized isocratic pump and improved degassing efficiency in OMNISEC RESOLVE offers unrivalled flow rate stability to reduce baseline noise in all detectors
- Integrated column oven in OMNISEC RESOLVE maintains a stable separation temperature, all the way up to 65°C
- Autosampler with zero injection volume overhead mode prevents wastage of your most precious samples, and can cool fragile samples to 4°C to protect them from aggregation and degradation
- OMNISEC REVEAL's light scattering detector is the most sensitive available enabling measurements of molecular weights as low as 200 Da and injection masses as low as 100 ng
- The self-balancing differential viscometer in OMNISEC REVEAL has user exchangeable capillaries to make it more robust and usable than any other available
- Combine data from multiple detectors to calculate hydrodynamic radius (Rh), radius of gyration (Rg), and Mark-Houwink parameters
- SEC-MALs detector that can be used to measure the absolute molecular weight of proteins, synthetic and natural polymers, as well as molecular size expressed as the radius of gyration, Rg.
*UHPLC - ultrahigh performance liquid chromatography
*UPLC - ultra performance liquid chromatography... Read More |
| Quantity | EA |
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