| Description | Method scouting is a process where different mobile phases and column stationary phases are evaluated to determine the best set of separation conditions for a particular sample. Manual solvent preparation, column switching, and method programming are time-consuming steps, so the Nexera method Method scouting is a process where different mobile phases and column stationary phases are evaluated to determine the best set of separation conditions for a particular sample. Manual solvent preparation, column switching, and method programming are time-consuming steps, so the Nexera method scouting system was developed to streamline the entire process for more efficient method development.
The system is based around 2 LC-30AD pumps, each with a quaternary valve, which allows the analyst to run binary gradients with 16 different solvent pairs. A high-pressure column selection valve holds from 1 to 6 columns, resulting in up to 96 unique separation conditions per sample. Ultra-high speed conditions can be easily transferred to conventional conditions using a transfer program. In addition, scouting is performed automatically when the mobile phase is switched.
The Nexera Method Scouting Solution software has intuitive, user-friendly screens to set the pump and column valve positions, gradient program steps, and it automatically builds the sequence table in seconds. Method Scouting Solution provides the data required for analysis via a graphical user interface, as well as automated controls conforming to laboratory operations configured in the system settings.
... Read More | The analysis of amino acids plays an important role not only in the food industry, but also in natural product and pharmaceutical fields. This system uses detection by post-column fluorescence derivatization, with o-phthalaldehyde (OPA) / N-acetylcysteine as the reaction reagent, to selectively and The analysis of amino acids plays an important role not only in the food industry, but also in natural product and pharmaceutical fields. This system uses detection by post-column fluorescence derivatization, with o-phthalaldehyde (OPA) / N-acetylcysteine as the reaction reagent, to selectively and with high sensitivity quantitate the amino acids contained in samples with high levels of contaminants.
Features
- Selectively detects amino acids based on Shimadzu's highly acclaimed post-column reaction technology and high-sensitivity fluorescence detector.
Detects amino acids with over ten times higher sensitivity than the ninhydrin method (UV detection), by using a derivatization method that provides selective reaction with amino radicals, together with fluorescence detection.
- Outstanding Reproducibility
Because derivatization occurs after separation in the column, reactions are not affected by the sample matrix. Therefore, analyses can be performed with good precision.
- Easy to Operate
Since column eluant is automatically derivatized by mixing it with the reaction reagent, it saves time and tedious tasks.
- The mobile phase and reaction solution are available as a kit, which means solutions can be prepared with minimal fuss.
... Read More | The CBM-40 is a small-profile unit that stacks neatly with main system components. Other LC modules connect via fiber optic cables for easy "plug and play" system configuration. An internal web server offers convenient control and monitoring of the UHPLC system through a web browser, LabSolutions The CBM-40 is a small-profile unit that stacks neatly with main system components. Other LC modules connect via fiber optic cables for easy "plug and play" system configuration. An internal web server offers convenient control and monitoring of the UHPLC system through a web browser, LabSolutions CDS, or other third-party software.
Features:
- Connection via Ethernet
- Offers 4 Fiber Optic ports for controlling other system components
... Read More | The modular LC-40 system is the workhorse for everyday HPLC, whether using traditional 5 micron fully porous LC columns or the popular SPP column phases for high efficiency separations with lower back pressures. With Analytical Intelligence functions, the system makes lab management simple, enablingThe modular LC-40 system is the workhorse for everyday HPLC, whether using traditional 5 micron fully porous LC columns or the popular SPP column phases for high efficiency separations with lower back pressures. With Analytical Intelligence functions, the system makes lab management simple, enabling users to easily review instrument status, optimize resource allocation, and achieve higher throughput.
Key features and benefits include:
- High efficiency chromatography with 44 MPa (~6,000 psi) pressure tolerance and LPGE or HPGE solvent delivery
- Ultra-fast injection cycles (7 sec) with ultralow carryover
- High capacity sample handling
- Optional dual-injection system
- Outstanding baseline stability and linearity (2.5 AU), even under fluctuating temperatures
- Plate changers enable non-stop temperature-controlled analysis of thousands of samples
- Allows remote monitoring in real time directly from a web browser or smart device
- Touch-panel interface allows the user to control the instrument and carry out analysis preparation directly without the need for a PC
- Analytical intelligence functions, including smart flow control, automatic startup, auto-recovery and auto-diagnostics, and real-time mobile phase monitoring
- i-PeakFinder tool – can automatically recognize peaks even in complex chromatograms with high noise, and accounts for baseline drift for higher integration accuracy
- i-PDeA II peak deconvolution function – can quantify peaks that cannot be completely separated by a column
... Read More | Enables Both HPLC and UHPLC Analysis
The Nexera-i MT is a new addition to the i-Series lineup. It enables both conventional analysis via its high compatibility with existing LC systems and rapid analysis via high-speed methods. In pharmaceutical development, a single integrated system allows Enables Both HPLC and UHPLC Analysis
The Nexera-i MT is a new addition to the i-Series lineup. It enables both conventional analysis via its high compatibility with existing LC systems and rapid analysis via high-speed methods. In pharmaceutical development, a single integrated system allows process synthesis screening analysis for synthetic substances in the UHPLC flow line, and impurity content identification in the HPLC flow line.
Analysis results from LC systems in the same laboratory may differ, even with the same method, due to differences in the volumes of these systems. The Nexera-i MT demonstrates outstanding reproducibility between various LC systems with different system volumes, simplifying method transfer between instruments.
Further more, with the Nexera-i MT the process of migrating from UHPLC to HPLC or from HPLC to UHPLC can be accomplished using a single system. The Nexera-i MT is based on the same user-friendly i-Series, but maximizes performance and reliability for migrating and transferring customer methods.... Read More |