Maldi Mass Spectrometer (Maldi MS)

Matrix-assisted laser desorption/ionization (MALDI) is a so-called “soft” ionization technique that has found widespread use in biological mass spectrometry. Soft ionization techniques enable the ionization of large biological molecules (such as proteins) without fragmenting them, meaning they can be analyzed intact. In the case of MALDI MS, the molecules to be analyzed (for instance, a collection of tryptic peptides) are mixed with an organic compound called a matrix, spotted and dried (crystallized) on the surface of a metal target plate. Upon irradiation with laser light, the matrix absorbs the energy and converts it to heat, which then causes the sample to ionize and explode off the plate into the mass analyzer. Though most often associated with time-of-flight (TOF) mass analyzers, MALDI sources can be coupled to other types of analyzer as well, including triple quadrupoles. Whatever the configuration, MALDI mass spectrometers have the advantage that, because the sample is archived on a plate, it can be analyzed and reanalyzed at leisure.
CompanyShimadzuShimadzuShimadzuShimadzuShimadzu
ItemAXIMA-iD Plus Microorganism AnalysisAxima Assurance MALDI Time of Flight Mass SpectrometerAxima Confidence MALDI TOF Mass SpectrometerAxima Performance MALDI TOF TOF Mass SpectrometerMegaTOF Megadalton MALDI Mass Spectrometer
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Catalog NumberAXIMA-iD PlusAXIMA AssuranceAxima ConfidenceAxima PerformanceMegaTOF
Price
Mass AnalyzerMALDI-TOF MSTOFTOFTOF/TOFTOF
Ionization Method(s)MALDIMALDIMALDIMALDIMALDI
DescriptionCertain microorganisms can cause severe diseases and considerable damage, and need to be identified quickly and reliably. The easy-to-use AXIMA-iDPlus Microbial Identification System is the ideal tool to address these concerns. With AXIMA-iDPlus, cultured microorganisms can be directly applied to ... Read More

An affordable, robust option for laboratories requiring routine manual or automated analysis of a wide variety of sample classes, the AXIMA Assurance provides high-quality, rapid MALDI mass spectra and an array of software tools for data processing and reporting. Incorporating a variable repetition

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An affordable, robust option for routine sample analysis performed manually or automatically, the AXIMA Confidence offers reliable mass information and MS/MS-derived structural detail. A linear mode enables outstanding levels of analysis of high-molecular weight samples while the reflectron mode,

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The AXIMA Performance is one of the most powerful tools in mass spectrometry, delivering information-rich spectra with greater sensitivity and higher confidence in identification. Extremely versatile, this MALDI TOF-TOF mass spectrometer utilizes state-of-the-art high energy MS/MS, delivers

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The MegaTOF has been developed by optimizing the integration of a high-performance Shimadzu linear MALDI TOF mass spectrometer with a CovalX high-mass system, allowing outstanding detection of macromolecules up to 1,500 kDa.

Features
  • Ultrahigh sensitivity
  • Detects macromolecules up to 1,500,000 Da
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Mass RangeInquire1 kDa to 500 kDa1 kDa to 500 kDa1 kDa to 500 kDa0.01 to 1.5 Mda
ResolutionInquire>5000 FWHM5000 FWHM in linear mode; 15000 FWHM in reflectron mode>20,000 FWHM (Reflectron mode)180 to 200 kDa
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