Time of Flight Mass Spectrometer (TOF MS)

Time-of-flight mass spectrometers (TOF MS) do exactly what their name suggests: determine an ion’s mass-to-charge ratio (m/z) based on how long it takes for that ion to travel down the instrument’s “flight tube” and reach the detector. Frequently, though not exclusively coupled to matrix-assisted laser desorption ionization (MALDI) sources, TOF MS come in a variety of configurations, including a single-stage time-of-flight mass spectrometer, a multi-stage TOF/TOF, and even a hybrid quadrupole-TOF (Q-TOF) instrument; the latter two enable MS/MS applications. Often, time-of-flight mass spectrometers contain two detectors: a linear detector at the end of the flight tube, and a “reflector” detector, which captures ions that were redirected back towards the source by a “reflectron.” The reflectron serves two purposes: correcting for discrepancies in initial kinetic energy of identically sized molecules (which would cause them to reach the detector at different times and thus, have different apparent m/z values) and lengthening the flight path, improving resolution.

Find, compare, and request a quote for time of flight mass spectrometers across leading suppliers at Labcompare; including access to product citations, related published figures, and first-hand reviews from our scientific community.

CompanyShimadzuShimadzuShimadzuShimadzuShimadzu
ItemLCMS-9030 Q-TOF Mass SpectrometerAxima Assurance MALDI Time of Flight Mass SpectrometerAxima Confidence MALDI TOF Mass SpectrometerAxima Performance MALDI TOF TOF Mass SpectrometerMegaTOF Megadalton MALDI Mass Spectrometer
Citations
(5)
Figures
(3)
Catalog NumberLCMS-9030AXIMA AssuranceAxima ConfidenceAxima PerformanceMegaTOF
Price
Ionization Method(s)ESI, APCI, DUIS, MicroMALDIMALDIMALDIMALDI
Mass AnalyzerQuadrupole Time-of-Flight (Q-TOF)TOFTOFTOF/TOFTOF
Resolution30,000 FWHM>5000 FWHM5000 FWHM in linear mode; 15000 FWHM in reflectron mode>20,000 FWHM (Reflectron mode)180 to 200 kDa
Scanning SpeedUp to 100 HzInquireInquireInquire15 sec/position
Mass Rangem/z 10 to 40,0001 kDa to 500 kDa1 kDa to 500 kDa1 kDa to 500 kDa0.01 to 1.5 Mda
DescriptionThe LCMS-9030 quadrupole time-of-fight (Q-TOF) mass spectrometer integrates the world’s fastest and most sensitive quadrupole technology with TOF architecture. A product of Shimadzu's engineering DNA, speed and effortless performance enable the LCMS-9030 to address qualitative and quantitative ... Read More

An affordable, robust option for laboratories requiring routine manual or automated analysis of a wide variety of sample classes, the AXIMA Assurance provides high-quality, rapid MALDI mass spectra and an array of software tools for data processing and reporting. Incorporating a variable repetition

... Read More

An affordable, robust option for routine sample analysis performed manually or automatically, the AXIMA Confidence offers reliable mass information and MS/MS-derived structural detail. A linear mode enables outstanding levels of analysis of high-molecular weight samples while the reflectron mode,

... Read More

The AXIMA Performance is one of the most powerful tools in mass spectrometry, delivering information-rich spectra with greater sensitivity and higher confidence in identification. Extremely versatile, this MALDI TOF-TOF mass spectrometer utilizes state-of-the-art high energy MS/MS, delivers

... Read More
The MegaTOF has been developed by optimizing the integration of a high-performance Shimadzu linear MALDI TOF mass spectrometer with a CovalX high-mass system, allowing outstanding detection of macromolecules up to 1,500 kDa.

Features
  • Ultrahigh sensitivity
  • Detects macromolecules up to 1,500,000 Da
... Read More
QuantityEAEAEAEAEA
Get Quote

Articles