| Description | The MegaTOF has been developed by optimizing the integration of a high-performance Shimadzu linear MALDI TOF mass spectrometer with a CovalX high-mass system, allowing outstanding detection of macromolecules up to 1,500 kDa.
Features
- Ultrahigh sensitivity
- Detects macromolecules up to 1,500,000 Da
The MegaTOF has been developed by optimizing the integration of a high-performance Shimadzu linear MALDI TOF mass spectrometer with a CovalX high-mass system, allowing outstanding detection of macromolecules up to 1,500 kDa.
Features
- Ultrahigh sensitivity
- Detects macromolecules up to 1,500,000 Da
- Stabilization of molecule using crosslinking reagent kits
- Fast, specific stabilization of protein interactions
- Also applicable for low mass applications
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Applications
- Antibody characterization
- Protein complexes characterization
- Therapeutic protein aggregates
- High mass MALDI imaging
- Inhibitors of protein-protein interactions
This product is only available in the United States.... Read More | An affordable, robust option for laboratories requiring routine manual or automated analysis of a wide variety of sample classes, the AXIMA Assurance provides high-quality, rapid MALDI mass spectra and an array of software tools for data processing and reporting. Incorporating a variable repetition An affordable, robust option for laboratories requiring routine manual or automated analysis of a wide variety of sample classes, the AXIMA Assurance provides high-quality, rapid MALDI mass spectra and an array of software tools for data processing and reporting. Incorporating a variable repetition rate 50Hz N2 laser, it is ideally suited for high-throughput QA/QC analysis of oligonucleotide/primers, synthetic peptides/proteins, polymers, and other small molecules.
Features:
High Sensitivity/Resolution:
A variable repetition rate 50 Hz N2 laser and advanced ion optics for enhanced ion transmission enable users to meet all sample throughput requirements. Pulsed extraction of ions from the MALDI source improves resolution, and enhanced calibration algorithms with easy-to-use software provide more accurate data.
Positive and Negative Ion Modes Included as Standard:
Allows greater flexibility and extends the compound categories that may be analyzed.
Patented Beam Blanker:
Removes unwanted low mass ions and prevents detector saturation.
Unparalleled Flexibility:
A variety of sample target formats, including standard microtiter plate format 96 or 384 well targets, can be used. In addition, Fleximass™ microscope slides (plain or 48 well targets) and a wide variety of adaptors for unconventional sample layouts are available.
Like all AXIMA MALDI-TOF systems, the AXIMA Assurance can be fully integrated with robotic sample preparation devices, including the AccuSpot MALDI plate spotter and CHIP chemical printer, to create application-specific platforms. Integration with the CHIP creates a powerful platform for tissue imaging, while using an AXIMA instrument with a Prominence GPC system and AccuSpot results in a fully automated platform for polymer analysis that delivers quick, detailed analysis of ultra-trace substances.
... Read More | An affordable, robust option for routine sample analysis performed manually or automatically, the AXIMA Confidence offers reliable mass information and MS/MS-derived structural detail. A linear mode enables outstanding levels of analysis of high-molecular weight samples while the reflectron mode, An affordable, robust option for routine sample analysis performed manually or automatically, the AXIMA Confidence offers reliable mass information and MS/MS-derived structural detail. A linear mode enables outstanding levels of analysis of high-molecular weight samples while the reflectron mode, incorporating the patented, newly improved curved-field reflectron, provides high resolution and mass accuracy.
Features:
High Sensitivity/Resolution
A variable repetition rate 50 Hz N2 laser and advanced ion optics for enhanced ion transmission enable users to meet all sample throughput requirements. Pulsed extraction of ions from the MALDI source, in combination with the unique reflectron design, improves resolution, and enhanced calibration algorithms with easy-to-use software provide more accurate data.
Easily Perform MS/MS
A seamless approach isolates ions of interest, and data-rich fragment ion spectra are quickly and simply acquired. The curved field reflectron design augments the low mass fragment region to provide additional information.
Positive and Negative Ion Modes Included as Standard
Allows greater flexibility and extends the compound categories that may be analyzed.
Patented Beam Blanker
Removes unwanted low mass ions and prevents detector saturation.
Unparalleled Flexibility
A variety of sample target formats, including standard microtiter plate format 96 or 384 well targets, can be used. In addition, Fleximass™ microscope slides (plain or 48 well targets) and a wide variety of adaptors for unconventional sample layouts are available.
Like all AXIMA MALDI-TOF systems, the AXIMA Confidence can be fully integrated with robotic sample preparation devices, including the AccuSpot MALDI plate spotter and CHIP chemical printer, to create application-specific platforms. Integration with the CHIP creates a powerful platform for tissue imaging, while using an AXIMA instrument with a Prominence GPC system and AccuSpot results in a fully automated platform for polymer analysis that delivers quick, detailed analysis of ultra-trace substances.
... Read More | The LCMS-9030 quadrupole time-of-fight (Q-TOF) mass spectrometer integrates the world’s fastest and most sensitive quadrupole technology with TOF architecture. A product of Shimadzu's engineering DNA, speed and effortless performance enable the LCMS-9030 to address qualitative and quantitative The LCMS-9030 quadrupole time-of-fight (Q-TOF) mass spectrometer integrates the world’s fastest and most sensitive quadrupole technology with TOF architecture. A product of Shimadzu's engineering DNA, speed and effortless performance enable the LCMS-9030 to address qualitative and quantitative challenges with genuine confidence and ease.
Reproducible Results
The LCMS-9030 Q-TOF delivers outstanding mass accuracy over a wide mass range, enabling users to consistently produce accurate identification results. In addition, the LCMS-9030 requires infrequent calibration, making it easy to achieve high mass accuracy over long periods.
High Sensitivity Detection
High efficiency ion guides, quadrupole, and collision cell enable high sensitivity for the detection of trace level compounds. And, due to its robust platform, the LCMS-9030 achieves reproducible quantitative analysis over longer periods of time.
Ultrafast Performance
The LCMS-9030 incorporates the patented ultrafast technologies used in Shimadzu LC-MS/MS platforms to deliver outstanding speed. Innovative TOF architecture enables precise, ultra-fast pulsing of ions into the flight tube and ideal reflection back to the detector. The result is high-speed data acquisition compatible with the high-throughput laboratory.
Compatibility with Multiple Ionization Units
In addition to the standard ESI ionization unit, optional APCI and Dual Ion Source (DUIS) probes are available. The DUIS offers an efficient combination of ESI and APCI ionization capabilities. In addition, a Micro-ESI 9030 interface brings microflow analysis to the LCMS-9030.
LabSolutions LCMS is your single point of control for UHPLC and Q-TOF mass spectrometry data acquisition and analysis. Qualitative and quantitative acquisition modes that fully utilize the capability of the LCMS-9030 are MS, SIM, MS/MS, MRM, and MS/MS (DDA).... Read More | The LCMS-9050 quadrupole time-of-flight mass spectrometer inherits the world-class mass accuracy and stability of the LCMS-9030 while incorporating newly developed UFstabilization technology for simultaneous positive ion/negative ion analysis with high mass accuracy at even higher speeds. Ease of The LCMS-9050 quadrupole time-of-flight mass spectrometer inherits the world-class mass accuracy and stability of the LCMS-9030 while incorporating newly developed UFstabilization technology for simultaneous positive ion/negative ion analysis with high mass accuracy at even higher speeds. Ease of use is evident throughout the system from mass calibration to maintenance, allowing the LCMS-9050 to be used easily in any scenario that requires accurate mass spectrometry.
Key features/benefits:
- Stable long-term mass accuracy with a high-precision temperature control system that inhibits even tiny mass variations caused by external factors
- Achieves consistent mass accuracy values, even when samples are analyzed successively in both positive and negative ion modes; this significantly reduces the time required for stabilization and analysis for improved analytical throughput
- Fast, stable polarity switching through incorporation of proprietary high-precision electrical circuitry and the UFstabilization™ algorithm (patent pending)
- Ultrafast data acquisition rates
- Requires only a small sample size for identification of unknowns
- Auto-tuning function that uses a standard sample to automatically correct mass accuracy, resolution, sensitivity, and other parameters
- Easy maintenance; the desolvation line and the ESI capillary can be replaced quickly and easily without breaking vacuum, minimizing downtime
LabSolutions Insight Explore™ software manages and processes data on the LCMS-9050 system. It enables library searching, structural analysis, composition estimation, multivalent ion analysis, and quantitative analysis of target compounds. The software organizes and presents analysis results clearly in one easy-to-read screen.... Read More |