Time of Flight Mass Spectrometer (TOF MS)

Time-of-flight mass spectrometers (TOF MS) do exactly what their name suggests: determine an ion’s mass-to-charge ratio (m/z) based on how long it takes for that ion to travel down the instrument’s “flight tube” and reach the detector. Frequently, though not exclusively coupled to matrix-assisted laser desorption ionization (MALDI) sources, TOF MS come in a variety of configurations, including a single-stage time-of-flight mass spectrometer, a multi-stage TOF/TOF, and even a hybrid quadrupole-TOF (Q-TOF) instrument; the latter two enable MS/MS applications. Often, time-of-flight mass spectrometers contain two detectors: a linear detector at the end of the flight tube, and a “reflector” detector, which captures ions that were redirected back towards the source by a “reflectron.” The reflectron serves two purposes: correcting for discrepancies in initial kinetic energy of identically sized molecules (which would cause them to reach the detector at different times and thus, have different apparent m/z values) and lengthening the flight path, improving resolution.

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CompanyShimadzuShimadzu
ItemAxima Performance MALDI TOF TOF Mass SpectrometerMegaTOF Megadalton MALDI Mass Spectrometer
Citations
(5)
Figures
(3)
Catalog NumberAxima PerformanceMegaTOF
Price
Ionization Method(s)MALDIMALDI
Mass AnalyzerTOF/TOFTOF
Resolution>20,000 FWHM (Reflectron mode)180 to 200 kDa
Scanning SpeedInquire15 sec/position
Mass Range1 kDa to 500 kDa0.01 to 1.5 Mda
Description

The AXIMA Performance is one of the most powerful tools in mass spectrometry, delivering information-rich spectra with greater sensitivity and higher confidence in identification. Extremely versatile, this MALDI TOF-TOF mass spectrometer utilizes state-of-the-art high energy MS/MS, delivers

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The MegaTOF has been developed by optimizing the integration of a high-performance Shimadzu linear MALDI TOF mass spectrometer with a CovalX high-mass system, allowing outstanding detection of macromolecules up to 1,500 kDa.

Features
  • Ultrahigh sensitivity
  • Detects macromolecules up to 1,500,000 Da
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QuantityEAEA
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