Quadrupole mass spectrometers are perhaps the simplest of mass spec instruments. Functioning effectively like a radio, the quadrupole MS – so-named because of its four charged rods, which run parallel to the flight paths of the ions it measures – filter ions by mass-to-charge ratio (m/z) by altering the voltages in the rods. Quadrupole mass spectrometers are available in a variety of formats, including a single quadrupole mass spectrometer, a triple quadrupole MS (three quadrupoles arranged in tandem), and a Q-TOF (a triple quad variant in which the third quadrupole is replaced with a time-of-flight mass analyzer).
Quadrupole mass analyzers are often used for targeted, quantitative applications and can be used either to measure one or a few given ions in a mixture, or to scan across a range of m/z values. Depending on the configuration, they can facilitate both MS and MS/MS applications. For instance, in a triple-quadrupole mass spectrometer, you can select ions for analysis in the first quadrupole, fragment them by collision with a gas in the second quadrupole, and analyze the resulting fragmentation ions in the third quadrupole.
Find, compare, and request a quote for quadrupole mass spectrometers across leading suppliers at Labcompare; including access to product citations, related published figures, and first-hand reviews from our scientific community.
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Company | Thermo Fisher Scientific | Thermo Fisher Scientific | Thermo Fisher Scientific | Thermo Fisher Scientific | Thermo Fisher Scientific |
Item | Thermo Scientific™ ISQ™ 7610 Single Quadrupole GC-MS System | Orbitrap Astral Mass Spectrometer | Thermo Scientific™ ISQ™ EM Single Quadrupole Mass Spectrometer | Thermo Scientific™ TSQ™ 9610 Triple Quadrupole GC-MS/MS System | TSQ Quantis™ MD Mass Spectrometer |
Catalog Number | IQLAAAGAAJFALOMBNA | Orbitrap Astral Mass Spectrometer | IQLAAAGADIFZZZMZZZ | IQLAAAGABNFARPMBNB | IQLAAEGAAXFAQTMBLA |
Price | | | | | |
Ionization Method(s) | EI, FS, SIM, FS/SIM, CI, PCI, NCI, depending on model | Adjustable heated electrospray ionization (HESI) probe | Atmospheric pressure ionization (API) source with interchangeable HESI and APCI probes | Varies by model, AEI, EI, CI | Inquire |
Mass Analyzer | Triple off-axis Thermo Scientific™ DynaMax™ XTEND XR detection system, with off-axis 10 kV dynode, discrete dynode electron multiplier and electrometer, linear from 0 to 110 µA | Orbitrap mass analyzer ranging from 7,500 to 480,000 resolution at m/z 200
Astral mass analyzer is operated at a single resolution setting of 80,000 at m/z 524 | Single quadrupole | Triple quadrupole | Triple quadrupole |
Scanning Speed | Inquire | Up to 200 Hz | Up to 20,000 Da/sec. | Inquire | Inquire |
Mass Range | 1.2–1100 u with Unit Mass Resolution | Maximum Astral mass analyzer resolution up to 80,000 FWHM at m/z 524
Maximum Orbitrap mass analyzer resolution of up to 480,000 FWHM at m/z 200 | 10 to 2000 m/z with Unit Mass Resolution | Inquire | 5 to 3000 m/z |
Description | Developed to enhance user experience in their workflows, the ISQ 7610 GC-MS system is streamlined to ensure great data consistency over time while offering automated instrument control tools. | Inquire | Adding mass spectrometry (MS) to your liquid chromatography (LC) analyses gives you access to the valuable data that only MS can provide. The new, easy-to-use ISQ™ EM Single Quadrupole Mass Spectrometer seamlessly integrates with LC systems for reliable, robust, and easy LC-MS routine analysis with Adding mass spectrometry (MS) to your liquid chromatography (LC) analyses gives you access to the valuable data that only MS can provide. The new, easy-to-use ISQ™ EM Single Quadrupole Mass Spectrometer seamlessly integrates with LC systems for reliable, robust, and easy LC-MS routine analysis with an extended mass range for more flexibility. Detect and quantify a variety of analytes by choosing to use either heated electrospray ionization (HESI) or atmospheric pressure chemical ionization (APCI). Integrated software allows both novices and experts to quickly master MS to gain more insights from every sample.... Read More | The TSQ 9610 GC-MS/MS system is designed to revolutionize laboratory productivity by delivering unprecedented levels of performance and reduce cost per sample for the high-throughput environment. | Develop in vitro diagnostic tests for demanding quantitative analyses leveraging the enhanced sensitivity and remarkable speed and robustness of the Thermo Scientific™ TSQ Altis™ MD Series Mass Spectrometer. The TSQ Altis MD Series mass spectrometer, a Class I medical device, offers superb Develop in vitro diagnostic tests for demanding quantitative analyses leveraging the enhanced sensitivity and remarkable speed and robustness of the Thermo Scientific™ TSQ Altis™ MD Series Mass Spectrometer. The TSQ Altis MD Series mass spectrometer, a Class I medical device, offers superb analytical performance and features the maximum usability, sensitivity and robustness required for laboratory developed tests (LDTs) from clinical diagnostic laboratories. With superb analytical performance, this platform features maximum usability, sensitivity, and robustness.... Read More |
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