Quadrupole Mass Spectrometer (MS) / Quadrupole Mass Analyzer

Quadrupole mass spectrometers are perhaps the simplest of mass spec instruments. Functioning effectively like a radio, the quadrupole MS – so-named because of its four charged rods, which run parallel to the flight paths of the ions it measures – filter ions by mass-to-charge ratio (m/z) by altering the voltages in the rods. Quadrupole mass spectrometers are available in a variety of formats, including a single quadrupole mass spectrometer, a triple quadrupole MS (three quadrupoles arranged in tandem), and a Q-TOF (a triple quad variant in which the third quadrupole is replaced with a time-of-flight mass analyzer).

Quadrupole mass analyzers are often used for targeted, quantitative applications and can be used either to measure one or a few given ions in a mixture, or to scan across a range of m/z values. Depending on the configuration, they can facilitate both MS and MS/MS applications. For instance, in a triple-quadrupole mass spectrometer, you can select ions for analysis in the first quadrupole, fragment them by collision with a gas in the second quadrupole, and analyze the resulting fragmentation ions in the third quadrupole.

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CompanyShimadzuShimadzuShimadzuShimadzuShimadzu
ItemLCMS-8050 Triple Quadrupole LC/MS/MS Mass SpectrometerGCMS-QP2020 NX Gas Chromatograph Mass Spectrometer (GC/MS)LCMS-2050 Mass SpectrometerLCMS-8060 NX Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-9050 Q-TOF Mass Spectrometer
Citations
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Figures
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Catalog NumberLCMS-8050GCMS-QP2020 NXLCMS-2050LCMS-8060 NXLCMS-9050
Price
Ionization Method(s)ESI, APCI, Dual IonizationEI, CI, NCIESI, APCI, Dual IonizationESI probe with focus electrodesESI, APCI, DUIS, Micro
Mass AnalyzerQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsMetal quadrupole with pre-rodSingle QuadrupoleTriple quadrupoleQuadrupole Time-of-Flight (Q-TOF)
Scanning Speed30,000 u/sec20,000 u/sec15,000 u/secMax. 30,000 u/sec (in all scan modes)
(0.1 u step: 300,000 data points/sec)
Inquire
Mass Range2 to 2000 m/z1.5 to 1090 m/zInquirem/z 2 to 2,000Inquire
DescriptionIncorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050 offers outstanding measurement speeds and quantitative performance. Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated ... Read MoreAdopting a proprietary multi-function ion source and a new large-capacity turbomolecular pump with heightened exhaust efficiency for all carrier gases including nitrogen, the rugged, high-sensitivity GCMS-QP2020 NX elevates GCMS performance to a new level. New Quick-CI and Smart SIM functionality ... Read MoreThe LCMS-2050 single quadrupole mass spectrometer combines the user-friendliness of an LC detector with the excellent performance of MS to provide a complete package of easy-to-use high-level performance and compactness. To make it accessible to all users, the system is enhanced with technology and ... Read MoreShimadzu's most powerful tandem mass spectrometer, the triple quad LCMS-8060NX utilizes proprietary technologies and more efficient ion transfer to achieve outstanding speed and sensitivity. Incorporation of a new IonFocus electrospray unit and newly designed ion guides deliver robust operation ... Read MoreThe LCMS-9050 quadrupole time-of-flight mass spectrometer inherits the world-class mass accuracy and stability of the LCMS-9030 while incorporating newly developed UFstabilization technology for simultaneous positive ion/negative ion analysis with high mass accuracy at even higher speeds. Ease of ... Read More
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