Q-TOF mass spectrometers combine TOF and quadrupole instruments, a pairing that results in high mass accuracy for precursor and product ions, strong quantitation capability, and fragmentation experiment applicability. The Q-TOF MS uses a quadrupole (four parallel rods arranged in a square formation), a collision cell, and a time of flight unit to produce spectra. Lighter ions accelerate faster down the flight tube to the detector, thus determining the ions’ mass-to-charge ratios. Q-TOF MS systems have MS-MS capabilities and can be coupled to GC or LC systems. Ion sources include MALDI, ESI, APCI, and APPI. Speed and sensitivity are hallmarks of the quadrupole TOF MS, with detection reaching low-femtogram levels. Their speed and suitability for quantitative analysis make these hybrid instruments a popular choice for chemists building combinatorial libraries. They are also widely used in drug discovery, clinical research, forensic toxicology, food safety, and environmental screening.
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| Company | Shimadzu | Shimadzu |
| Item | LCMS-9050 Q-TOF Mass Spectrometer | LCMS-9030 Q-TOF Mass Spectrometer |
| Citations | | |
| Catalog Number | LCMS-9050 | LCMS-9030 |
| Price | | |
| Description | The LCMS-9050 quadrupole time-of-flight mass spectrometer inherits the world-class mass accuracy and stability of the LCMS-9030 while incorporating newly developed UFstabilization technology for simultaneous positive ion/negative ion analysis with high mass accuracy at even higher speeds. Ease of The LCMS-9050 quadrupole time-of-flight mass spectrometer inherits the world-class mass accuracy and stability of the LCMS-9030 while incorporating newly developed UFstabilization technology for simultaneous positive ion/negative ion analysis with high mass accuracy at even higher speeds. Ease of use is evident throughout the system from mass calibration to maintenance, allowing the LCMS-9050 to be used easily in any scenario that requires accurate mass spectrometry.
Key features/benefits:
- Stable long-term mass accuracy with a high-precision temperature control system that inhibits even tiny mass variations caused by external factors
- Achieves consistent mass accuracy values, even when samples are analyzed successively in both positive and negative ion modes; this significantly reduces the time required for stabilization and analysis for improved analytical throughput
- Fast, stable polarity switching through incorporation of proprietary high-precision electrical circuitry and the UFstabilization™ algorithm (patent pending)
- Ultrafast data acquisition rates
- Requires only a small sample size for identification of unknowns
- Auto-tuning function that uses a standard sample to automatically correct mass accuracy, resolution, sensitivity, and other parameters
- Easy maintenance; the desolvation line and the ESI capillary can be replaced quickly and easily without breaking vacuum, minimizing downtime
LabSolutions Insight Explore™ software manages and processes data on the LCMS-9050 system. It enables library searching, structural analysis, composition estimation, multivalent ion analysis, and quantitative analysis of target compounds. The software organizes and presents analysis results clearly in one easy-to-read screen.... Read More | The LCMS-9030 quadrupole time-of-fight (Q-TOF) mass spectrometer integrates the world’s fastest and most sensitive quadrupole technology with TOF architecture. A product of Shimadzu's engineering DNA, speed and effortless performance enable the LCMS-9030 to address qualitative and quantitative The LCMS-9030 quadrupole time-of-fight (Q-TOF) mass spectrometer integrates the world’s fastest and most sensitive quadrupole technology with TOF architecture. A product of Shimadzu's engineering DNA, speed and effortless performance enable the LCMS-9030 to address qualitative and quantitative challenges with genuine confidence and ease.
Reproducible Results
The LCMS-9030 Q-TOF delivers outstanding mass accuracy over a wide mass range, enabling users to consistently produce accurate identification results. In addition, the LCMS-9030 requires infrequent calibration, making it easy to achieve high mass accuracy over long periods.
High Sensitivity Detection
High efficiency ion guides, quadrupole, and collision cell enable high sensitivity for the detection of trace level compounds. And, due to its robust platform, the LCMS-9030 achieves reproducible quantitative analysis over longer periods of time.
Ultrafast Performance
The LCMS-9030 incorporates the patented ultrafast technologies used in Shimadzu LC-MS/MS platforms to deliver outstanding speed. Innovative TOF architecture enables precise, ultra-fast pulsing of ions into the flight tube and ideal reflection back to the detector. The result is high-speed data acquisition compatible with the high-throughput laboratory.
Compatibility with Multiple Ionization Units
In addition to the standard ESI ionization unit, optional APCI and Dual Ion Source (DUIS) probes are available. The DUIS offers an efficient combination of ESI and APCI ionization capabilities. In addition, a Micro-ESI 9030 interface brings microflow analysis to the LCMS-9030.
LabSolutions LCMS is your single point of control for UHPLC and Q-TOF mass spectrometry data acquisition and analysis. Qualitative and quantitative acquisition modes that fully utilize the capability of the LCMS-9030 are MS, SIM, MS/MS, MRM, and MS/MS (DDA).... Read More |
| Ionization Method(s) | ESI, APCI, DUIS, Micro | ESI, APCI, DUIS, Micro |
| Mass Analyzer | Quadrupole Time-of-Flight (Q-TOF) | Quadrupole Time-of-Flight (Q-TOF) |
| Mass Range | Inquire | m/z 10 to 40,000 |
| Scanning Speed | Inquire | Up to 100 Hz |
| Resolution | Inquire | 30,000 FWHM |
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