LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ LC-MS/MS Mass SpectrometerThermo Scientific™ EA IsoLink™ IRMS SystemThermo Scientific™ Orbitrap Eclipse™ Tribrid™ Mass SpectrometerThermo Scientific™ Orbitrap IQ-X™ Tribrid™ Mass Spectrometer
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Catalog NumberIQLAAEGAAPFALGMBDKIQLAAMGAATFAQMMZZZIQLAAEGAAPFADBMBKSIQLAAEGAAPFADBMBMA
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Ionization Method(s)APCI, H-ESIInquireInquireInquire
Mass AnalyzerHybrid Quadrupole / OrbitrapInquireInquireInquire
Scanning SpeedUp to 12 HzInquireOTMSn up to 40 Hz ITMSn up to 45 HzInquire
Resolutionup to 280,000 FWHMInquire7500 to 500,000 (FWHM) at m/z 2007500 to 500,000 (FWHM) at m/z 200
DescriptionTake Quanfirmation™ to the next level. The Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer introduced the revolutionary concept of Quanfirmation. The Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer takes Quanfirmation to the next level with increased ... Read MoreDiscover an automated, easy-to-use solution for µg- to mg-level elemental and isotope analysis with the Thermo Scientific™ EA IsoLink™ IRMS System. This all-in-one isotope ratio mass spectrometry system enables laboratories to increase sample throughput, reduce cost per sample, and provides high-... Read MoreOne system, maximum insights
Today’s cutting-edge research pushes LC-MS to its limits. Obtaining high confidence insights to enable accurate resolution of subtle differences and avoid costly dead-ends is needed faster than ever before. The Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer
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Built for small-molecule analyses, the Thermo Scientific™ Orbitrap IQ-X™ Tribrid™ mass spectrometer reveals your most complex chemical structures? with ultimate confidence, ease, and experimental versatility.
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