LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™ Exactive™ Plus EMR Orbitrap™ LC-MS SystemThermo Scientific™ GasBench Plus SystemThermo Scientific™ Orbitrap Eclipse™ Tribrid™ Mass SpectrometerThermo Scientific™ Orbitrap IQ-X™ Tribrid™ Mass SpectrometerThermo Scientific™ TSQ Quantis™ Triple Quadrupole Mass Spectrometer
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Catalog NumberIQLAAEGAAPFALGMBDLIQLAAMGAATFAETMBMZIQLAAEGAAPFADBMBKSIQLAAEGAAPFADBMBMAIQLAAEGAAXFZZZMZZZ
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Ionization Method(s)APCI, H-ESIInquireInquireInquireInquire
Mass AnalyzerOrbitrapInquireInquireInquireInquire
Scanning SpeedUp to 12 HzInquireOTMSn up to 40 Hz ITMSn up to 45 HzInquireInquire
Resolutionup to 140,000 FWHMInquire7500 to 500,000 (FWHM) at m/z 2007500 to 500,000 (FWHM) at m/z 200Inquire
DescriptionWhile analysis of denatured proteins may be the most common LC/MS protein analysis, many biopharmaceutical and biological research applications require analysis of proteins in their native (intact) state. The Thermo Scientific™ Exactive™ Plus EMR mass spectrometer combines unsurpassed high-... Read MoreExpand the applications of isotope ratio mass spectrometry (IRMS) with the Thermo Scientific™ GasBench Plus System. This universal on-line gas preparation and introduction system provides a robust solution for high-precision on-line isotope and molecular ratio determination of gaseous samples via ... Read MoreOne system, maximum insights
Today’s cutting-edge research pushes LC-MS to its limits. Obtaining high confidence insights to enable accurate resolution of subtle differences and avoid costly dead-ends is needed faster than ever before. The Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer
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Built for small-molecule analyses, the Thermo Scientific™ Orbitrap IQ-X™ Tribrid™ mass spectrometer reveals your most complex chemical structures? with ultimate confidence, ease, and experimental versatility.The TSQ Quantis MS seamlessly integrates with industry-leading quantitation software, HPLCs and UHPLCs, and sample preparation solutions; it also offers enhanced efficiency during targeted quantitation workflows for a wide array of molecular species. Other benefits include:
  • Superb sensitivity that
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QuantityEAEAEAEAEA
TypeInquireContinuous Flow IRMSInquireInquireInquire
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