LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™ EA IsoLink™ IRMS SystemThermo Scientific™ Exactive™ Plus EMR Orbitrap™ LC-MS SystemThermo Scientific™ Orbitrap Eclipse™ Tribrid™ Mass SpectrometerThermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass SpectrometerThermo Scientific™ TSQ Quantis™ Triple Quadrupole Mass Spectrometer
Citations
Catalog NumberIQLAAMGAATFAQMMZZZIQLAAEGAAPFALGMBDLIQLAAEGAAPFADBMBKSIQLAAEGAAPFADBMBHQIQLAAEGAAXFZZZMZZZ
Price
Ionization Method(s)InquireAPCI, H-ESIInquireHESIInquire
Mass AnalyzerInquireOrbitrapInquireOrbitrapInquire
Scanning SpeedInquireUp to 12 HzOTMSn up to 40 Hz ITMSn up to 45 HzInquireInquire
ResolutionInquireup to 140,000 FWHM7500 to 500,000 (FWHM) at m/z 2007500-500,000 (FWHM) at m/z 200Inquire
DescriptionDiscover an automated, easy-to-use solution for µg- to mg-level elemental and isotope analysis with the Thermo Scientific™ EA IsoLink™ IRMS System. This all-in-one isotope ratio mass spectrometry system enables laboratories to increase sample throughput, reduce cost per sample, and provides high-... Read MoreWhile analysis of denatured proteins may be the most common LC/MS protein analysis, many biopharmaceutical and biological research applications require analysis of proteins in their native (intact) state. The Thermo Scientific™ Exactive™ Plus EMR mass spectrometer combines unsurpassed high-... Read MoreOne system, maximum insights
Today’s cutting-edge research pushes LC-MS to its limits. Obtaining high confidence insights to enable accurate resolution of subtle differences and avoid costly dead-ends is needed faster than ever before. The Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer
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Excel at the most challenging of applications, including low level PTM analysis, multiplexed relative quantitation using isobaric tags, intact protein characterization, as well as MSn analysis of small molecules with the new Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer. This... Read MoreThe TSQ Quantis MS seamlessly integrates with industry-leading quantitation software, HPLCs and UHPLCs, and sample preparation solutions; it also offers enhanced efficiency during targeted quantitation workflows for a wide array of molecular species. Other benefits include:
  • Superb sensitivity that
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QuantityEAEAEAEAEA
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