LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanySCIEXSCIEXSCIEXSCIEXSCIEX
ItemSelexION Differential Mobility SpectrometryEcho® MS systemIntabio ZT systemSCIEX Triple Quad 7500 systemX500R QTOF system
Citations
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(1)
Catalog NumberSelexIONEcho MSIntabio ZTSCIEX Triple Quad 7500X500R QTOF
Price
Ionization Method(s)InquireElectrospray IonizationInquireOptiFlow® Pro Ion SourceTurbo V ion source with twin sprayer ESI probe
and twin sprayer APCI probe
Mass AnalyzerInquireInquireInquireTriple quadrupoleQTOF
Scanning SpeedInquireUp to 3 samples per secondInquire20,000 Da/sUp to 25 Hz (25 spectra per second)
ResolutionInquireInquireInquireUp to 3100 for mass 922 in LIT mode 1000 Da/s (0.3 Da)
Tune to a peak width of 0.5 Da for TQ mode
Equal to or greater than 42,000 (FWHM) measured on the (M+6H)6+ charge isotope cluster for bovine insulin at m/z 956
DescriptionLC-MS/MS assay development can be challenging, particularly for analytes that coelute with contaminants or become buried within background noise. The SCIEX SelexION Differential Mobility Separation device (DMS) provides an extra level of selectivity so you can resolve difficult analytes and achieve ... Read MoreThis ultra-high sample throughput system for Acoustic Ejection Mass Spectrometry (AEMS) delivers speed, scale and reproducibility with unyielding data quality. The Echo® MS System leverages industry leading quantitative MS technology from SCIEX to deliver a highly sensitive solution that can ... Read MoreThe Intabio ZT system couples icIEF separation and UV detection with high-resolution mass spectrometry on the ZenoTOF 7600 system. Experience one integrated workflow with a single, accessible dataset containing the required information to make the right decisions, fast.

Features
  • Comprehensive
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Incomparable: Experience extraordinary sensitivity gains from the SCIEX 7500 system. Start detecting the previously undetectable, and quantify at lower levels with impressive precision.

Ingenious: Expand your laboratory capabilities to test dirty and complex samples. The new D Jet ion guide will
... Read More
Engineered for standard biotherapeutic characterization analyses, the X500B QTOF system is a true benchtop instrument, with streamlined processing to get to a consistent, accurate view of your biologic. It is optimized for intact mass analysis, subunit analysis as well as high-quality peptide ... Read More
QuantityInquireEAEAEAEA
TypeInquireInquireInquireLC-MS/MSInquire
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