LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™ Orbitrap™ Ascend Tribrid™ mass spectrometerThermo Scientific™ ISQ™ EC Single Quadrupole Mass SpectrometerThermo Scientific™ Orbitrap Eclipse™ Tribrid™ Mass SpectrometerThermo Scientific™ Orbitrap Exploris™ 480 Mass SpectrometerThermo Scientific™ TSQ Quantis™ Triple Quadrupole Mass Spectrometer
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Catalog NumberIQLAAEGAAPFADBMBNGIQLAAAGADIFZZZMZZZIQLAAEGAAPFADBMBKSIQLAAEGAAPFARBMBKRIQLAAEGAAXFZZZMZZZ
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Ionization Method(s)InquireAPI, HESIInquireInquireInquire
Mass AnalyzerInquireSingle quadrupoleInquireInquireInquire
Scanning SpeedInquireUp to 20,000 Da/sec.OTMSn up to 40 Hz ITMSn up to 45 HzInquireInquire
Resolution7500 to 480,000 (FWHM) at m/z 200Inquire7500 to 500,000 (FWHM) at m/z 200480,000 at m/z 195Inquire
DescriptionScale your science for protein and biopharmaceutical characterization. Increased throughput, versatility, and ease-of-use, the Thermo Scientific™ Orbitrap™ Ascend Tribrid mass spectrometer accelerates proteomics and native protein analyses.Add mass spectrometry (MS) to your IC and LC analyses for access to the valuable data that only MS can provide. The new, easy-to-use Thermo Scientific™ ISQ™ EC Single Quadrupole Mass Spectrometer seamlessly integrates with ion chromatography (IC) and high performance liquid chromatography (HPLC) ... Read MoreOne system, maximum insights
Today’s cutting-edge research pushes LC-MS to its limits. Obtaining high confidence insights to enable accurate resolution of subtle differences and avoid costly dead-ends is needed faster than ever before. The Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer
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Making genius simpler
Empowering life science researchers to translate each experimental step to a new level of insight with a next-generation ownership experience coupled with an intelligence-driven experimental approach. With the Thermo Scientific Orbitrap Exploris 480 mass spectrometer you'll
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The TSQ Quantis MS seamlessly integrates with industry-leading quantitation software, HPLCs and UHPLCs, and sample preparation solutions; it also offers enhanced efficiency during targeted quantitation workflows for a wide array of molecular species. Other benefits include:
  • Superb sensitivity that
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QuantityEAEAEAEAEA
TypeInquireSeamless integration with IC or LCInquireInquireInquire
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