LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyShimadzuShimadzuShimadzu
ItemLCMS-8050 Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-8060 NX Triple Quadrupole LC/MS/MS Mass SpectrometerNexera Mikros Microflow Liquid Chromatography Mass Spectrometer System
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Catalog NumberLCMS-8050LCMS-8060 NXNexera Mikros
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Ionization Method(s)ESI, APCI, Dual IonizationESI probe with focus electrodesInquire
Mass AnalyzerQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsTriple quadrupoleInquire
Scanning Speed30,000 u/secMax. 30,000 u/sec (in all scan modes)
(0.1 u step: 300,000 data points/sec)
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ResolutionR < 0.7 u FWHMR < 0.7 u FWHM and adjustable to 0.5 uInquire
DescriptionIncorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050 offers outstanding measurement speeds and quantitative performance. Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated ... Read MoreShimadzu's most powerful tandem mass spectrometer, the triple quad LCMS-8060NX utilizes proprietary technologies and more efficient ion transfer to achieve outstanding speed and sensitivity. Incorporation of a new IonFocus electrospray unit and newly designed ion guides deliver robust operation ... Read MoreCovering the complete range from micro (0.1 µL/min) to semi-micro (500 µL/min), Nexera Mikros allows operators to realize high sensitivity with the reliability and ruggedness of HPLC. A newly designed micro ESI source provides greater than ten times the sensitivity of standard UHPLC-MS ... Read More
QuantityEAEAEA
TypeInquireTriple Quad LC-MS/MSInquire
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