LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyShimadzuShimadzuShimadzuShimadzuShimadzu
ItemLCMS-8050 Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-2020 Single Quadrupole Mass SpectrometerLCMS-2050 Mass SpectrometerNexera Mikros Microflow Liquid Chromatography Mass Spectrometer SystemNexera QX Multiplex LC-MS
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Catalog NumberLCMS-8050LCMS-2020LCMS-2050Nexera MikrosNexera QX
Price
Ionization Method(s)ESI, APCI, Dual IonizationESI, APCI, Dual IonizationESI, APCI, Dual IonizationInquireInquire
Mass AnalyzerQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsSingle QuadrupoleSingle QuadrupoleInquireInquire
Scanning Speed30,000 u/sec15,000 u/sec15,000 u/secInquireInquire
ResolutionR < 0.7 u FWHMR = 2 MInquireInquireInquire
DescriptionIncorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050 offers outstanding measurement speeds and quantitative performance. Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated ... Read MoreUtilizing patented ultrafast (UF) technology, the LCMS-2020 mass spectrometer offers faster measurements and higher detection sensitivity for quicker and more accurate detection of trace impurities in a variety of applications.

Features
  • Ultrafast scanning speed of 15,000 u/sec, without
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The LCMS-2050 single quadrupole mass spectrometer combines the user-friendliness of an LC detector with the excellent performance of MS to provide a complete package of easy-to-use high-level performance and compactness. To make it accessible to all users, the system is enhanced with technology and ... Read MoreCovering the complete range from micro (0.1 µL/min) to semi-micro (500 µL/min), Nexera Mikros allows operators to realize high sensitivity with the reliability and ruggedness of HPLC. A newly designed micro ESI source provides greater than ten times the sensitivity of standard UHPLC-MS ... Read MoreThe Nexera QX Multiplex LC-MS/MS System uses multiple, alternating sample introduction streams for continuous operation of the mass spectrometer to significantly increase laboratory throughput and profitability.

  • Multiple stream technology eliminates waiting for column equilibration and system
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