Dissolution Apparatus / Dissolution Tester

Before a drug in tablet form can begin to work pharmacologically on a patient, it must first dissolve in the patient’s stomach before absorption into the bloodstream; this obvious first step can prove challenging to drug development. Dissolution apparatus is therefore necessary to provide information on the in vitro release of drugs in order to predict their in vivo behavior. There are seven USP-defined types of dissolution apparatus: baskets, paddles, reciprocating cylinders, flow through cells, paddle over disk types, cylinders, and reciprocating holders. Although USP 2 paddles are most widely used, most dissolution apparatus incorporate any number of each type (often all of them) . Dissolution apparatus – especially of the popular paddle variety – can suffer from hydrodynamic disturbances that can muddle test results; therefore, the customer should seek features that limit these disturbances, such as the motorized insertion and removal of the sampling cannula. While all available dissolution apparatus adhere to U.S. Pharmacopeia standards, only some adhere to U.S., European, and Japanese standards.
CompanyDistek, Inc.Distek, Inc.Distek, Inc.Distek, Inc.Distek, Inc.
ItemsensIR 3200 DisintegratorModel 2500 RTD Water Bath Dissolution SystemModel 2500 Select Bathless Dissolution SystemModel 2500 Water Bath DissolutionOpt-Diss 410 In-situ Fiber Optic UV System
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Catalog NumbersensIR 3200Model 2500 RTDModel 2500 SelectModel 2500Opt-Diss 410
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DescriptionDistek’s sensIR 3200 uses proven bathless heating to offer a disintegrator without the hassle and inconveniences associated with conventional water bath-based instruments. By eliminating the water bath and utilizing a sleek modular unit, Distek’s sensIR 3200 offers two, four, or six disintegration ... Read MoreOffering maximum flexibility and configurability, the Distek Model 2500 RTD Dissolution Test System with patent pending wireless temperature sensors, continuously monitors and displays the in-vessel temperature for each vessel. A brilliant touch screen and unparalleled command of the instrument with... Read MoreOffering maximum flexibility and configurability, the Distek Model 2500 Select - Bathless Dissolution System succeeds three generations of patented bathless technology. A brilliant touch screen and unparalleled command of the instrument with electronic tracking of serialized stirring elements, ... Read MoreOffering maximum flexibility and configurability, the Distek Model 2500 Dissolution System succeeds four generations of the user-friendly 2100 series. A brilliant touch screen and unparalleled command of the instrument with electronic manual, serial numbers, electronic qualification labels, ... Read MoreThe Distek Opt-Diss 410 in-situ fiber optic UV system measures directly in the vessel, eliminating the need for conventional sampling, and with-it consumables like filters, tubing and syringes, saving time, labor, and money. Moving light rather than liquids also allows generating near real-time ... Read More
Temperature Range20°C to 65°CAmbient to 55 °CAmbient to 99 °CAmbient to 55 °CInquire
Speed Range< 8 minInquireInquire30 to 300 rpmInquire
Dimensions2 Position - 14 x 19 x 28.5 in (WxDxH) 4 Position - 24 x 19 x 28.5 in (WxDxH) 6 Position - 27 x 19 x 28.5 in (WxDxH)(WxDxH) 27.5 x 19.5 x 38.5 in(WxDxH) 27.5 x 19.5 x 38.5 in(WxDxH) 25 x 19.5x 24 in(WxDxH) 13 x 22.5 x 22 in
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