Description
Available in a 3?µm particle size and formats such as 4.6?×?150?mm, 4.6?×?300?mm, 7.8?×?150?mm, and 7.8?×?300?mm, the Waters GTxResolve SEC?1000?Å Column is designed for high recovery analysis of large gene therapy biomolecules including Nucleic Acids & LNPs. Its low adsorption MaxPeak™ HPS hardware and bridged ethylene HO PEO particles provide long column lifetimes, reduced secondary interactions, and improved MALS sensitivity. Compared to traditional 5?µm, 1000?Å SEC columns, the 3?µm GTxResolve 1000?Å packing delivers enhanced resolution and reproducibility for biomolecules in the 200–800?Å size range, enabling clearer separation of aggregates, monomers, and ejected transgenes. This improvement supports more confident assessment of mRNA integrity, LNP heterogeneity, and viral vector impurity profiles.