3-Propyl-3-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-1,5-dioxaspiro[5.5]undecane-2,4-dione from Aladdin Scientific Corporation

Description3-Propyl-3-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-1,5-dioxaspiro[5.5]undecane-2,4-dione is a perfluorinated organic building block. It can be prepared by reacting octafluorotoluene, 3-propyl-1,5-dioxaspiro[5.5]-undecane-2,4-dione,N,N-diisopropylethylamine and CH3CN.This compound undergoes cycloreversion to form the fluoro(hetero)aryl ketene, which undergoes efficient coupling with nucleophiles and allows rapid incorporation of highly fluorinated α-fluoro(hetero)aryl acetic acid derivatives