At the Association for Diagnostics & Laboratory Medicine (ADLM) 2026 Annual Meeting, Waters announced the launch of the Xevo TQ Absolute XR IVD Mass Spectrometer—expanding its MassTrak IVD System portfolio of LC-MS/MS Systems with a solution that combines sensitivity and robustness for clinical applications.
The new system builds on the step-change performance of the Xevo TQ Absolute IVD Mass Spectrometer, which established the benchmark for sensitivity among IVD-compliant tandem quadrupole mass spectrometers.
Developed for routine laboratory testing requiring IVD-compliant systems, the Xevo TQ Absolute XR IVD System delivers exceptional trace-level analytical performance in complex biological matrices. With up to 5x greater sensitivity than other instruments in its class, the system enables lower limits of detection and reliable quantification of challenging analytes from smaller sample volumes. This enhanced sensitivity is critical for applications requiring accurate measurement at very low concentrations, such as low-level estradiol testing for women's health and hormone-related cancer assessment,and hair toxicologyfor detecting drugs of abuse and documenting long-term exposure.
Featuring the new StepWave XR Ion Guide, the Xevo TQ Absolute XR IVD System delivers improved robustness, enabling ion ratio consistency for up to 6x longer compared with the Xevo TQ Absolute IVD System. This advancement gives laboratories greater confidence in consistent performance when analyzing complex clinical samples containing phospholipids, salts, and other matrix components.
The new MassTrak LC-MS/MS IVD System includes the ACQUITY UPLC I-Class PLUS System with the Xevo TQ Absolute XR IVD Mass Spectrometer. The ACQUITY UPLC I-Class PLUS System is designed to deliver fast, accurate sample analysis that enhances mass spectrometer performance and simplifies the characterization of complex samples. Together, the integrated system delivers industry-leading sensitivity, enhanced robustness for complex sample matrices, and a user-friendly design that helps maximize laboratory uptime.