Wiley has released the new edition of the Wiley Registry/NIST Mass Spectral Library, a reference database that combines two essential mass spectrometry references in a single, integrated collection, giving scientists the full depth of both to identify unknown chemical compounds.
For years, laboratories doing GC-MS analysis have relied on Wiley’s renowned Wiley Registry of Mass Spectral Data and the NIST/EPA/NIH EI Mass Spectral Library from the U.S. government’s National Institute of Standards and Technology (NIST) to power their analytical workflows. These two respected references are united in this database, one of the most comprehensive resources of its kind.
The Wiley Registry/NIST Mass Spectral Library is part of Wiley’s growing portfolio of scientific data and research intelligence solutions, which spans spectral databases, chemistry and materials literature, and analytical tools supporting researchers from discovery through applied outcomes.
The new 2026 edition updates the collection, adding tens of thousands of newly validated compounds across both libraries and bringing the total to more than 1.2 million electron ionization (EI) mass spectra—unique chemical “signatures” used to identify substances.
Wiley’s spectral database solutions are trusted by leading pharmaceutical, environmental, and forensic laboratories worldwide, reflecting Wiley’s mission to transform knowledge into actionable intelligence that helps researchers make confident, high-stakes decisions.
Available in the most common instrumentation manufacturer formats, the library supports high-confidence analysis across GC-MS workflows.