Description
The Centro is a high-performance, easy to use luminometer for both, flash and glow luminescence applications. The optimized optical system provides lowest background and negligible crosstalk (10
-6). Due to its superior sensitivity (XS version: < 1.8 zmol firefly luciferase) and wide dynamic range (> 6 orders of magnitude), the Centro is ideally suited for all luminescent reporter gene assays, immunoassays (LIA, ILMA), cell-based and biochemical assays.
The Centro supports all basic luminescence technologies including:
- Flash-type Luminescence
- Glow-type Luminescence
- Cellular Luminescence
- Bio-Luminescence
- Chemi-Luminescence
Sensitive and reliable: Thanks to a stringent selection of photomultipliers working in photon counting mode and more than 40 years of experience building luminometers, the Centro provides highly sensitive luminescence detection: less than 5 amol ATP/well (25 fM) can be detected reliably. In the Centro XS, optics have been optimized to increase its sensitivity even further: below 1.8 amol ATP/well (9 fM).
Powerful crosstalk control – reliable results: With a crosstalk index of 10
-6, you never have to worry about the position of your high-intensity samples in your plate.
Integrated waste pump: Thanks to its built-in waste pump, you don’t need to worry about loading microplates, waste containers or removal of injector tips for washing and filling the reagent lines; the built-in waste pump takes care of the safe removal of excess liquids.
JET injectors: highest accuracy, speed and cell-friendliness. The Centro can be equipped with up to 3 JET injectors with variable volumes in pre-measurement or measurement position*. The ultra-fast injection speed of JET injectors eliminates any delay between injection and measurement and enables measurement of fast reactions, e.g. flash luminescence.
- Accurate pipetting of small volumina: JET injectors ensure the injection of large and small volumes with high accuracy and offer a precision of more than 98% over the entire volume range
- Cell-friendly performance: cell-friendly materials and negligible shear forces enable worry-free injection of cell suspensions, e.g. in Aequorin-based calcium assays
*
All injectors in pre-measurement position in the Centro XS.
Applications
- Reporter gene assays
- Aequorin-based calcium monitoring
- ATP determination
- Luminescent Immunoassays (LIA, ILMA)
- DNA probe assays
- SNP determination
- CALUX® Assays