HPLC Pump / Solvent Delivery System

When delivering smaller particles through the liquid mobile phase of a HPLC unit, the liquid must be forced through the column under pressure. The purpose of an HPLC pump, also called a solvent delivery system, is to force the liquid through the system while maintaining a specific flow rate. HPLC pumps can be broadly categorized into three types: syringe pumps that provide pulseless delivery, reciprocating or piston pumps that push the mobile phase through with a series of pistons, and pneumatic pumps that use gas to pressurize the mobile phase. Reciprocating pumps are most common due to their good pressure generation, constant flow rate, and small footprint, but each type of pump has its pros and cons that should be weighed when purchasing. Other things to look out for when selecting a pump include the instrument’s compatibility with different solvents, low dead volume to minimize issues with solvent changeover, delivery method (either isocratic or gradient), as well as things like price, ease of use, and lifetime.

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LC-20AP Large-scale Solvent Delivery Unit
Shimadzu
  • Type:
    Series-Type Double Plunger
  • Flow Rate:
    0.01 to 150.0 mL/min
  • Max. Pressure:
    42.0 Mpa
Citations:
(255)
LC-40B X3 HPLC/UHPLC Pump
Shimadzu
  • Type:
    Inquire
  • Flow Rate:
    0.1 uL/min to 10 mL/min
  • Max. Pressure:
    130 Mpa
Citations:
(9)
LC-40B XR HPLC/UHPLC Pump
Shimadzu
  • Type:
    Inquire
  • Flow Rate:
    0.1 uL/min to 10 mL/min
  • Max. Pressure:
    70 Mpa
Citations:
(11)
LC-40D HPLC/UHPLC Pump
Shimadzu
  • Type:
    Inquire
  • Flow Rate:
    0.1 uL/min to 10 mL/min
  • Max. Pressure:
    44 Mpa
Citations:
(36)
LC-40D X3 HPLC/UHPLC Pump
Shimadzu
  • Type:
    Inquire
  • Flow Rate:
    0.1 uL/min to 10 mL/min
  • Max. Pressure:
    130 Mpa
Citations:
(13)
LC-40D XS HPLC/UHPLC Pump
Shimadzu
  • Type:
    Inquire
  • Flow Rate:
    0.1 uL/min to 10 mL/min
  • Max. Pressure:
    105 Mpa
Citations:
(11)
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Shimadzu
LC-20AP
Scheme 3
2 Figures from 255 Publications
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