| Description | Preconfigured protocols and custom assay workflows simplify microplate data acquisition and analysis.
SoftMax® Pro Software is designed to provide the simplicity, flexibility and power required for advanced data analysis. It provides ready-to-run protocols, analysis algorithms, and 21 different Preconfigured protocols and custom assay workflows simplify microplate data acquisition and analysis.
SoftMax® Pro Software is designed to provide the simplicity, flexibility and power required for advanced data analysis. It provides ready-to-run protocols, analysis algorithms, and 21 different curve fit options. Every step is optimized for data acquired from a Molecular Devices microplate reader or data imported from another source to simplify analysis and reporting. Compliance tools are available for regulated laboratories providing end-to-end chain of custody.
Built-in protocols -
Use over 160 protocols with preconfigured assay parameters for a wide variety of common assays including protocols for our entire suite of reagents, SpectraTest® Validation Plates, and adapter plates.
Advanced reader control -
Build custom assay workflow, run multitask kinetics, and pause and resume kinetic reads with the discontinuous kinetics feature.
Flexible calculations -
Data analysis features are available such as 21 different curve fit options, simplified cross-plate analysis and interpolation, and automatic calculations of relative potency, EC50, and Z factors.
Project management made easy -
Group multiple plate reads in one protocol. Display results, conditional pass/fail statements, mini graphs, and images in the notes section for easy viewing of overall project results.
Secure electronic recordkeeping -
Controlled user access is provided through a granular permission structure and unique logins with electronic signature support for verification, authorization, and approval, including audit trails.
Validation tools reduce cost -
Extensive suite of microplate reader validation tools can reduce the cost and time of validation by 50% when compared to using multiple platforms to collect and analyze data.
Other features and benefits include: - Simplify data measurement
- Import and analyze complex data
- Publish like a pro
... Read More | Go from assay to insights quickly and reliably with ImageXpress imaging systems and IN Carta software.
IN Carta® Image Analysis Software solves complex image analysis problems utilizing advanced Artificial Intelligence (AI), transforming images into results, which can be interpreted with ease. UserGo from assay to insights quickly and reliably with ImageXpress imaging systems and IN Carta software.
IN Carta® Image Analysis Software solves complex image analysis problems utilizing advanced Artificial Intelligence (AI), transforming images into results, which can be interpreted with ease. User-friendly workflows help you get answers faster from 2D, 3D, and 4D experiments. With the integration of our Custom Module Editor application, you can define highly customized image analysis protocols allowing you to obtain robust results—even for complex assays—then quickly visualize, review, and interact with the analysis results. Let IN Carta software do the heavy lifting so you can focus on your research.
Features:
- Deep learning
Improve the specificity of your image analysis workflows by utilizing the SINAP module. SINAP relies on deep learning-based image analysis, resulting in robust segmentation for virtually any biological structure.
- AI-powered data analytics
Leverage the power of machine learning without being a data scientist. Identify and quantify phenotypic changes in a user-friendly workflow. Explore your data and reveal insights from complex datasets. Find novel and unexpected phenotypes with a few mouse clicks.
- 3D analysis
The Custom Module Editor’s 3D application provides unprecedented flexibility in segmenting complex biological structures. Image datasets can be acquired in 3D or 4D (time-lapse 3D), and tailored image analysis routines can be developed within a guided workflow.
- Start with a worklist
Browse to a parent directory and populate your worklist with image datasets of interest, or simply use search to find them.
- Customization
Browse and review images from experiments, create image analysis protocols of different complexity, and add on-demand data classification. Visualize analysis results using 360 ° data linking among images, data table and charts.
- Batch analysis and monitoring
Analyze multiple experiments in batch analysis mode with one or more analysis protocols. Monitor the status of all submitted tasks and oversee their progression in real time.
Flexi-Protocol
Flexi-Protocol application althe creation of custom analysis protocols of various complexity by adding as many analysis steps as needed. Each analysis step can contain image pre-processing and object mask post-processing operations to better adapt to a specific assay. Redesigned analysis and image viewer panes can be expanded or collapsed depending on where focus is needed.
IN Carta SINAP
SINAP is a module that uses deep learning algorithms to improvethe accuracy and reliability of high-content screening assays at the first step in the analysis pipeline—segmentation. It provides better object detection than traditional image analysis methods. Deep learning models can be easily tailored within a user-friendly tool, so that any novel biological objects can be segmented efficiently. Quantitative information extracted from segmented objects is more accurate, so errors are not propagated down the analysis pipeline.
IN Carta Phenoglyphs
The IN Carta® Phenoglyphs™ Software Module uses a unique combination of unsupervised and supervised machine learning to quantify phenotypical changes. Using many hundreds of cellular features that can be analyzed simultaneously, a comprehensive phenotypic profile is created and can be applied throughout an entire screening workflow. This multivariate approach to classification provides an accurate characterization of object populations, allowing users to resolve subtle phenotypic changes induced by drug treatment or genetic modification. It can be utilized across many biological targets, including organoids, cells, spheroids, and more.
IN Carta Custom Module Editor 2D and 3D
- Createa simple step-by-step custom analysis
- Tailor object segmentation and classification
- Find objects localized within defined biological compartments
- Report only the measurements required for an assay of interest
- Analyze live imaging data
- True 3D segmentation (3D application only)
- Robust reconstruction of 2D segmentation into volume for 3D assays (3D application only)
... Read More | High-content image analysis software featuring time lapse analysis.
MetaXpress® High-Content Image Acquisition and Analysis Software is a comprehensive solution for high-content analysis featuring a tightly orchestrated and integrated workflow. The portfolio of application modules supports a High-content image analysis software featuring time lapse analysis.
MetaXpress® High-Content Image Acquisition and Analysis Software is a comprehensive solution for high-content analysis featuring a tightly orchestrated and integrated workflow. The portfolio of application modules supports a range of needs from ease-of-use through to proprietary assay design. The software includes powerful and elegant tools for 2D and 3D imaging such as time lapse analysis. With the assistance of our acquisition setup wizard, you’ll be generating data in minutes.
Z-stacks and 3D volumetric analysis -
The integrated acquisition and analysis application modules for 3D cell models simplify high-throughput quantification of 3D structures with volume, intensity, and distance measurements.
Fast acquisition and analysis -
Easily captures fast biological functions with our patented fast frame rate that can capture 50 frames per second. A 1-color, 384-well plate analysis can be performed in a little as six minutes.
Intelligent segmentation -
Application modules feature turnkey image segmentation for label-free and fluorescently labeled images. The Custom Module Editor offers advanced tools for improved segmentation.
Scalable parallel processing -
MetaXpress PowerCore™ Software runs analysis routines in minutes. This optional module leverages the power of parallel processing to accelerate analysis.
Data management solution -
MDCStore™ Data Manager, included with MetaXpress software, organizes images, experimental information, and data analysis. It enables seamless manipulation of complex sets of images and metadata.
Advanced informatics -
AcuityXpress™ High-Content Informatics Software is an optional enterprise level platform for advanced data mining, analysis, statistics, and visualization. It shares the MDCStore database for seamless integration.
Other features and benefits include: - Acquire and analyze in 2D and 3D
- Streamline image analysis
- Design custom analyses easily
... Read More | Become compliant with FDA part 11 software validation.
SoftMax® Pro 7.1 GxP Software is the latest, most secure software to achieve full FDA 21 CFR Part 11 compliance with streamlined workflows to ensure data integrity. Every step is optimized to simplify analysis and reporting to support our Become compliant with FDA part 11 software validation.
SoftMax® Pro 7.1 GxP Software is the latest, most secure software to achieve full FDA 21 CFR Part 11 compliance with streamlined workflows to ensure data integrity. Every step is optimized to simplify analysis and reporting to support our microplate readers.
Our expert team will partner with you to set up single- or enterprise-level software, and provide IQ OQ services using our validation package to establish full compliance on your microplate readers. Major data privacy and security improvements support the latest GDPR regulations.
Windows Active Directory -
User administration in a Windows Active Directory or via the GxP Admin software simplifies defining password criteria, reset and change periods, and reduces the amount of IT support.
Improved auto-save functionality -
New documents must be saved before they can be modified and documents are automatically saved before and after a read to prevent the loss of data.
Improved signing process -
Users can only sign a single pre- and post-release statement per document contributing to data integrity.
Projects feature -
Project teams can be created where users can be assigned to different projects with different roles but can't have different roles in the same project.
Roles and permissions -
Permissions are defined on a per role basis and assigned accordingly to users within projects to maintain a structured system. Three predefined roles—Scientist, Lab Manager, Lab Technician—accommodate the document release workflow, allowing first-time users to get started quickly.
Auto-export function -
Data can be exported to a location outside the database and various file formats are available to support the import into other applications such as LIMS (Laboratory Information Management System) or SDMS (Scientific Data Management System). XML is supported for data export and auto export.
Other features and benefits include: - Track and record all changes
- Enable enterprise-level document sharing
- Maintain data integrity
... Read More |