Laboratory extruders are used to consistently process and shape material at a very precise level. Many laboratory extruders offer built-in homogenization systems to ensure proper particle size and sufficient throughput by reducing the need for a separate homogenization step. Laboratory extruders are commonly offered in two different configurations. Hand-operated extruders offer a cost-effective option for laboratories that only have the occasional need for extrusion or have limited space, while more robust extruders typically use either a mechanized or gas-powered system to perform the extrusion and offer more consistency and a hands-off operation. When comparing laboratory extruders ensure that the capacity is sufficient for your laboratories throughput. Also, ensure that the pressure range of the extruder is sufficient for the product that you will be extruding.
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| Company | Genizer LLC | Genizer LLC | Genizer LLC |
| Item | Liposome HandExtruder | Jacketed Liposome Extruder | Online Liposome Extruder |
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| Catalog Number | HandExtruder | GJE | GOE |
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| Description | The Genizer HandExtruder is a low-cost micro liposome extrusion tool. Two gas-tight syringes, an extrusion body and a stabilizing block are included. It facilitates liposome preparation with hands-on operation. The user can gradually push the plunger of the filled syringe to drive the sample throughThe Genizer HandExtruder is a low-cost micro liposome extrusion tool. Two gas-tight syringes, an extrusion body and a stabilizing block are included. It facilitates liposome preparation with hands-on operation. The user can gradually push the plunger of the filled syringe to drive the sample through the filter membrane within the extruder body, and then gently push the plunger to return the sample to the original syringe. To get a sample with uniform liposome sizes, the user can repeat these two steps five to ten times. Features - Cooling: jacketed thermo barrel (optional).
- Feed & Collection: Gas Tight Syringe, Hamilton.
- Spares: O-rings.
- Warranty period as long as one year against any manufacturing defects.
Advantages - Low-cost.
- Sanitary with 316L stainless steel.
- Efficient: micron pore supporting maximize pressure and lower the contamination.
- Compatibility: GMP and FDA compliant
... Read More | The Genizer Jacketed Liposome Extruder utilizes a nitrogen gas cylinder to force a drug, protein or gene liposome suspension via a track-etched membrane with a predetermined pore size; generally, 5–10 passes are enough to create a sample with consistent liposome size. The Genizer Jacketed Liposome The Genizer Jacketed Liposome Extruder utilizes a nitrogen gas cylinder to force a drug, protein or gene liposome suspension via a track-etched membrane with a predetermined pore size; generally, 5–10 passes are enough to create a sample with consistent liposome size. The Genizer Jacketed Liposome Extruders are designed to produce uniform unilamellar liposomes and lipopolyplexes with minimal dead volume. Features - Including: Large pore support screen, laser micro pore disc, high pressure nitrogen tubing G5/8.
- Spares: O-rings, outlet hose.
- Warranty period as long as one year against any manufacturing defects.
Advantages - Sanitary with 316L stainless steel.
- Efficient: micron pore supporting maximize pressure and lower the contamination.
- Compatibility: GMP and FDA compliant
... Read More | The Genizer Online Extruder combines with a high pressure homogenizer, which can help decrease the number of passes required to attain a perfect liposome size distribution and desired particle sizes since the homogenizer system (diamond interaction chamber) will help pre-treat the liposome sample toThe Genizer Online Extruder combines with a high pressure homogenizer, which can help decrease the number of passes required to attain a perfect liposome size distribution and desired particle sizes since the homogenizer system (diamond interaction chamber) will help pre-treat the liposome sample to the nanoscale.
Features - Including: Large pore support screen, laser micro pore disc.
- Spares: O-rings, outlet hose
- Warranty period as long as one year against any manufacturing defects.
Advantages - Sanitary with 316L stainless steel.
- Efficient: micron pore supporting maximize pressure and lower the contamination.
- Compatibility: GMP and FDA compliant
... Read More |
| Type | Manual | Compressed air-driven | Online |
| Pressure | Up to 200 psi | 500 – 800 psi (model dependent) | 2,500 – 3,000 psi (model dependent) |
| Material | Inquire | 316 L stainless steel, NBR | 316L stainless steel, NBR |
| Applications | Liposome extrusion | Liposome extrusion | Liposome extrusion |
| Capacity | 0.5 mL, 1.0 mL, 2.5 mL | 10 mL, 100 mL, 800 mL, 3,000 mL, 10,000 mL | 25 mL, 200 mL, 1000 mL, 8 L, 20 L |
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