| Description | Dual monochromators increase performance and assay flexibility.
The SpectraMax® M Series Multi-Mode Microplate Readers measure UV and visible absorbance, fluorescence, luminescence, fluorescence polarization, TRF and HTRF. Standard features include a cuvette port, spectral scanning in 1 nm Dual monochromators increase performance and assay flexibility.
The SpectraMax® M Series Multi-Mode Microplate Readers measure UV and visible absorbance, fluorescence, luminescence, fluorescence polarization, TRF and HTRF. Standard features include a cuvette port, spectral scanning in 1 nm increments, and up to six wavelengths per read. These robust readers have been placed in labs from Antarctica to the International Space Station.
With optimized reagents, validation tools, and industry-leading SoftMax® Pro Software, they provide consistent performance.
Patented optimization -
The patented AutoPMT optimization of the SpectraMax M5 reader adjusts the fluorescence detector to each sample well's concentration and normalizes the raw data, extending the dynamic range of assays.
IQ/OQ/PM Services -
Qualify Molecular Devices microplate readers in GLP or GMP environments with our IQ/OQ/PM Services to preserve the documentation of services in a compliant format that can be accessed remotely.
Validation tools -
Extensive suite of validation tools reduces the cost and time of validation by 50% as compared to using multiple platforms to collect and analyze data.
Compliance software -
SoftMax Pro GxP Software extends data acquisition and analysis solution into regulated laboratories working under GMP, GLP, and 21 CFR Part 11 for secure electronic records.
Other features and benefits include: - - Assay flexibility
- Better absorbance accuracy
- Increased throughput
... Read More | Unlimited breadth of user-upgradeable application modules expands research capabilities.
The SpectraMax® i3x Multi-Mode Microplate Reader measures absorbance, fluorescence, and luminescence with available upgrades including western blot, cell imaging, and fast kinetics with injectors plus Unlimited breadth of user-upgradeable application modules expands research capabilities.
The SpectraMax® i3x Multi-Mode Microplate Reader measures absorbance, fluorescence, and luminescence with available upgrades including western blot, cell imaging, and fast kinetics with injectors plus additional detection modes.
With the SpectraMax® MiniMax™ 300 Imaging Cytometer, industry-leading SoftMax® Pro Software, and user-configurable detection modules, the reader provides you with the ability to explore cellular pathways and protein expression on one microplate reader.
User-configurable applications -
User-configurable detection modules expand the reader’s detection capabilities to include AlphaScreen, Time-Resolved Fluorescence, HTRF, fast kinetics with injectors, western blot detection, and more.
No-stain cell analysis -
The StainFree™ Cell Detection Algorithm for brightfield cell segmentation enables cell counting and confluency measurement without destructive stains, simplifying the cell counting workflow.
Multi-channel functionality -
Two fluorescence detection channels on the MiniMax cytometer enable the analysis of cell viability or cell toxicity assays, including ratiometric assays like live-dead and transfection efficiency.
Cellular pathway analysis -
Cell confluence and cell viability imaging, western blot analysis, and quantitation of nucleic acids and protein, can be captured on one reader.
Other features and benefits include: - Capture flash assays with ease
- Reduce background noise
- Increase fluorescence performance
... Read More | Run everyday assays, explore new applications, and spend less time on setup and analysis. The SpectraMax® iD3s and iD5e Multi-Mode Microplate Readers bring absorbance, fluorescence, and luminescence detection together on one platform, with intuitive tools and optional capabilities that support Run everyday assays, explore new applications, and spend less time on setup and analysis. The SpectraMax® iD3s and iD5e Multi-Mode Microplate Readers bring absorbance, fluorescence, and luminescence detection together on one platform, with intuitive tools and optional capabilities that support your laboratory’s changing needs.
Choose the SpectraMax iD3s reader for core assay workflows, with a tunable monochromator that lets you select wavelengths to match your assays. For more advanced applications, the SpectraMax iD5e reader adds hybrid monochromator and filter-based optics, time-resolved fluorescence (TRF), and tunable fluorescence polarization (FP), with optional support for TR-FRET, including HTRF®, BRET, and western blot detection.
Both readers offer optional dual injectors for assays requiring reagent addition during measurement. Temperature control, multiple shaking modes, and an optional CO2/O2 gas mixer support live-cell and microbial growth experiments. SoftMax® Pro Software connects assay setup, data acquisition, and analysis, helping you turn measurements into interpretable results.
Features:
- Run multiple assay types on one platform – Perform ELISA, nucleic acid and protein quantitation, cell viability, and microbial assays using one reader and a common software platform. The iD5e reader supports additional applications, including optional western blot detection.
- Spend less time setting up and analyzing assays – Get started with more than 200 preconfigured protocols in SoftMax Pro Software. Intuitive setup and integrated analysis tools help reduce repetitive work and support consistent workflows across experiments.
- Support fast kinetic assays with consistent reagent mixing – Optional dual injectors with SmartInject® Technology deliver and mix reagents in the well for flash and other time-sensitive assays. Reverse Prime functionality helps recover unused reagent from injector tubing, reducing waste.
- Match detection settings to demanding assays – The iD5e reader’s hybrid optical system combines monochromator wavelength flexibility with filter-based sensitivity. An ultra-cooled photomultiplier tube helps reduce detector noise, supporting the measurement of weak signals.
- Control conditions during live-cell and microbial experiments – Multiple shaking modes and an optional, user-installable CO2/O2 gas mixer help you establish conditions suited to your cells or microorganisms during kinetic and longer-duration studies.
- Simplify filter setup when switching assays – On the iD5e reader, automatic filter identification uses NFC technology to recognize installed filters, making it easier to check the available filters when configuring an experiment.
- Maintain controlled temperatures throughout your assay – Temperature regulation from 5°C above ambient to 66°C supports temperature-sensitive reactions and growth studies, helping you maintain consistent measurement conditions.
- Optimize signal collection for your samples – Adjustable read height lets you optimize the position of the detection optics for your assay conditions, helping improve signal collection across different plate formats and sample volumes.
- Conserve precious samples and expand measurement formats – Measure samples in volumes of 2–4 µL with the optional SpectraDrop Micro-Volume Microplate, or use the SpectraCuvette™ Adapter Plate for compatible cuvette-based measurements on the same reader.
- Access routine workflows more quickly – Use touchscreen Quick Read icons to start common measurements and a personalized protocol library to access frequently used methods, simplifying setup for repeated experiments.
- Add western blot detection to your reader – Expand the iD5e reader with the optional enhanced TRF module to support western blot detection and low-abundance protein quantitation. Extended signal stability offers greater flexibility in detection timing, with sensitivity dependent on assay design and configuration.
... Read More |
| Reading Modes | Absorbance, Fluorescence, Luminescence,Time-Resolved Fluorescence, Fluorescence Polarization, HTRF | Absorbance, Fluorescence (top/bottom read), Luminescence (top read), Time-Resolved Fluorescence (top read), Fluorescence Polarization (top read), HTRF (top read), AlphaScreen (top read) | Absorbance, Fluorescence (top/bottom read), Luminescence (top/bottom read), Time-Resolved Fluorescence (top/bottom read), Fluorescence Polarization (top/bottom read), HTRF (top/bottom read), HTRF |