| Description | RoboLector Platform Overview
The RoboLector XL system is an automated fermentation platform which combines the high-throughput fermentation and online monitoring capability of the BioLector XT microbioreactor with the precise and accurate liquid handling of a robotic system.
The RoboLector system RoboLector Platform Overview
The RoboLector XL system is an automated fermentation platform which combines the high-throughput fermentation and online monitoring capability of the BioLector XT microbioreactor with the precise and accurate liquid handling of a robotic system.
The RoboLector system autonomously prepares media compositions, among others, from the design of experiments (DoE) tests, followed by an online-monitored high-throughput cultivation.
Furthermore, pH adjustments can be made and inducers as well as feed solutions can be added to each cultivation well according to a pre-defined schedule or triggered by online process signals. Automated sampling into various targets including a cooling station facilitates optimal process monitoring and control.
Features of the RoboLector XL
Cultivation Modes - DO or time controlled feeding
- Fed-batch with bolus feeding
- Repeated fed-batch
- Biomass dependent sampling or dosing
- Time dependent sampling or dosing
- pH adjustments
Online Trigger Signals - Biomass concentration
- pH, DO (using optodes)
- Fluorescent molecules (GFP, YFP, DsRed ...)
- NAD(P)H and riboflavins
- Process or induction time
- Working volume
Advantages - Automated upstream processing of up to 48 parallel cultivations
- Continuous operation 24 hours/day and 7 days/week
- Plug & Play disposable technology
- Design of experiments (DoE)• Detailed process understanding in short time
- Excellent pipetting accuracy (< 5 %, 50 - 950 µl) and reproducibility (CV < 5 %, 50 - 950 µl)
- Reliable scale-up to lab-fermenters
- Fast and easy data analysis
- A valuable tool for PAT and QbD
- Processing units possible (for custom made solutions)
Applications - Automated sampling
- Automated induction
- Induction profiling
- Synchronized process manipulation
- pH profiling
- Feeding profiling
- Media preparation
- Process characterization
- High-throughput protein expression
- Automated upstream processing with microbial cultures
... Read More | Optimize dependability and walk-away time. The Biomek i5 is a recent addition to our liquid handling portfolio, representing the best of what has made Biomek an industry-leading brand - combined with enhancements suggested by customers around the globe. - Ideal for medium- to high-throughput
Optimize dependability and walk-away time. The Biomek i5 is a recent addition to our liquid handling portfolio, representing the best of what has made Biomek an industry-leading brand - combined with enhancements suggested by customers around the globe. - Ideal for medium- to high-throughput workflows
- 25 deck positions
- 0.5 µL-1,000 µL (Multichannel) or 0.5 µL-5,000 µL (Span-8) pipetting volume ranges
- Single Multichannel head (96/384) or Span-8 pipetting with gripper
Features of the Biomek i5 Automated Workstation Versatile Workspace - Open platform with grid-based deck
- Internal LED light illuminates workspace
- Automated Labware Positioners (ALPs) for sample processing
- Optional enclosed version to protect samples from airborne particles
- Integrate additional devices on- or off-deck
- Configurable for specific applications
Flexible Pipetting & Workflow Management - Multichannel head (96/384) or Span-8 pipetting
- Large-volume 1 mL multichannel pipetting head
- High-access, rotating gripper with unique offset finger design
- Disposable & fixed Biomek tips, including septum piercing
- Transfer volumes from 0.5 µL - 5,000 µL
- Independent Span-8 probe calibration
- 8 channel liquid-level sensing
- Supports labware from tubes to 1,536-well microplates
- Accurate intra-well pipetting
Simple System Operation - Easily automate existing processes and execute quick workflow changes
- Powered by icon-based software with data tracking and LIMS connectivity
- Windows 10 OS
- Extend walk-away operation with process management and scheduling software
- Automated deck framing
- Data-driven operations including hit-picking & normalization
- Light curtain safety feature
- Instrument status light bar
- DeckOptix cameras for live, remote-monitoring & on-error video capture
Application-Focused Solutions - Consultative workflow analysis
- Expert application & technical support
- Biomek automated demonstrated methods & capabilities for genomic, drug discovery & basic research workflows
... Read More | The most powerful and comprehensive Biomek available. - High-throughput
- 45 deck positions
- 0.5 - 5,000 µL pipetting volume range
- Single or dual heads
Biomek i7 Automated Workstation Features Versatile Workspace - Spacious, open-platform with grid-based deck
- Up to 45 deck positions
- Internal LED
The most powerful and comprehensive Biomek available. - High-throughput
- 45 deck positions
- 0.5 - 5,000 µL pipetting volume range
- Single or dual heads
Biomek i7 Automated Workstation Features Versatile Workspace - Spacious, open-platform with grid-based deck
- Up to 45 deck positions
- Internal LED light
- Automated Labware Positioners (ALPs) for sample processing
- Optional enclosed version to protect samples from airborne particles
- Integrate additional devices on- or off-deck
- Configurable for specific applications
Flexible Pipetting and Workflow Management - Multiple single- & dual-arm configurations with Multichannel heads (96/384/Pin tool) and/or Span-8 pipetting
- Large-volume 1 mL multichannel pipetting head
- High-access, rotating gripper(s) with unique offset finger design
- Disposable & fixed Biomek pipette tips (including septum piercing)
- Transfer volumes from 0.5 µL - 5,000 µL
- Independent Span-8 probe calibration
- 8 channel liquid-level sensing
- Supports labware from tubes to 1,536-well microplates
- Accurate intra-well pipetting
Simple System Operation - Easily automate existing processes & execute quick workflow changes
- Powered by icon-based software with data tracking & LIMS connectivity
- Windows 10 OS
- Extend walk-away operation with process management and scheduling software
- Guided system setup
- Automated deck framing
- Data-driven method operations including hit-picking & normalization
- Light curtain safety feature
- Instrument status light bar
- DeckOptix cameras for live, remote-monitoring & on-error video capture
Application-focused Solutions - Consultative workflow analysis
- Expert application & technical support
- Biomek-automated demonstrated methods & capabilities for genomic, drug discovery & basic research workflows
... Read More |
| Applications | Automated sampling, automated induction, induction profiling, synchronized process manipulation, pH profiling, feeding profiling, media preparation, process characterization, high-throughput protein expression, and automated upstream processing with microbial cultures | Genomic, drug discovery & basic research | Genomic, drug discovery & basic research workflows |