Fractionation can be caused by a variety of chemical, biological, or physical processes and is employed in various areas of science, engineering and technology.
Fractionation systems are designed to separate an analyte from a sample into equal portions or fractions. It does so in accordance with either the analytes physical or chemical properties, such as by size, density, or bonding ability. In column chromatography, for example, fractionation occurs by difference of affinity whereas in cell fractionation, the cells components are fractioned out by difference in mass. Fractionation instruments provide hands-off, programable, and repeatable options for separating desired samples.
Find, compare, and request a quote for fractionation systems across leading suppliers at Labcompare; including access to product citations, related published figures, and first-hand reviews from our scientific community.
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| Company | Biocomp Instruments | Biocomp Instruments | Biocomp Instruments | Biocomp Instruments |
| Item | Piston Gradient Fractionator | Gradient Master | Gradient Master / Piston Gradient Fractionator Hybrid System | Triax Flow Cell |
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| Description | The world's highest resolution gradient fractionator using top-down piston displacement. A computer-driven stepper motor descends a piston from the top, displacing gradient layers through the patented Trumpet Tip™. Capable of recovering gradient slices as small as 10 microns thick with visible band The world's highest resolution gradient fractionator using top-down piston displacement. A computer-driven stepper motor descends a piston from the top, displacing gradient layers through the patented Trumpet Tip™. Capable of recovering gradient slices as small as 10 microns thick with visible band detection down to ribosome-scale particles.... Read More | The Gradient Master™ generates linear gradients using a patented process called tilted tube rotation. Starting with empty tubes, you can form 6 identical gradients in as little as 10 minutes, producing gradients more reproducible than any other gradient forming technique. Solutes supported include The Gradient Master™ generates linear gradients using a patented process called tilted tube rotation. Starting with empty tubes, you can form 6 identical gradients in as little as 10 minutes, producing gradients more reproducible than any other gradient forming technique. Solutes supported include sucrose, glycerol, tartarate, Optiprep®, Nycodenz®, Ficoll®, Percoll®, Metrizamide, Renografin®, NaCl, CsCl, NaAc, KCl and more.... Read More | Hybrid instrument combining the Gradient Master™ gradient former and Piston Gradient Fractionator™ in a single unit (Model 153 Gradient Station). Gradient forming uses patented tilted tube rotation; fractionation uses a computer-driven piston with patented Trumpet Tip™ for top-down displacement Hybrid instrument combining the Gradient Master™ gradient former and Piston Gradient Fractionator™ in a single unit (Model 153 Gradient Station). Gradient forming uses patented tilted tube rotation; fractionation uses a computer-driven piston with patented Trumpet Tip™ for top-down displacement fractionation with high resolution.... Read More | Patent-pending UV and fluorescence flow cell for gradient profiling. Records absorbance from 0 to 5 OD linearly at 0.0001 OD resolution (non-linear to 20 OD). Simultaneously records UV absorbance and fluorescence profiles. Unique geometry eliminates bubbles and automatically aligns profiles at the Patent-pending UV and fluorescence flow cell for gradient profiling. Records absorbance from 0 to 5 OD linearly at 0.0001 OD resolution (non-linear to 20 OD). Simultaneously records UV absorbance and fluorescence profiles. Unique geometry eliminates bubbles and automatically aligns profiles at the meniscus.... Read More |
| Type | Piston Gradient Fractionator | Gradient Former | Hybrid Gradient Former and Fractionator | UV/Fluorescence Flow Cell for Gradient Profiling |
| Applications | High-resolution density gradient fractionation; polysome analysis; virus purification; ribosome subunit isolation; particle sedimentation analysis; phage capsid assembly studies | Density gradient centrifugation; linear gradient formation; rate zonal and isopycnic separations; polysome analysis; virus purification; ribosome analysis | Density gradient centrifugation; linear gradient formation; high-resolution gradient fractionation; polysome analysis; virus purification; ribosome analysis; band visualization | Gradient profiling; polysome analysis; UV absorbance monitoring; fluorescence detection during fractionation; simultaneous UV and fluorescent profile recording |
| Detector(s) | Inquire | Inquire | Inquire | UV absorbance detector; visible light fluorescence detector (simultaneous dual-channel recording) |
| Wavelength Filters | Inquire | Inquire | Inquire | UV (254 nm standard for nucleic acid/protein detection); visible light excitation for fluorescence: compatible with EGFP, mCherry, Alexa 488, 555, 568, Cy2, Cy3, Cy3.5, Cy5, mKate2 and others |
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