C18 columns are HPLC (high performance liquid chromatography) columns that use a C18 substance as the stationary phase. C18 HPLC columns are used in environmental sciences and chemical analysis, as well as industries such as pharmaceutical and environmental sciences, to analyze individual parts of chemical mixtures. C18 stationary phases are not identical from one C18 HPLC column to another. C18 simply means that the molecules contain 18 carbon atoms, so the other atoms in the molecule can vary, leading to significantly different substances. Knowing the characteristics of the compounds that will be run through the C18 columns can help you choose which one will work best for you. A C18 column can come in many sizes, with or without an end cap, with different particle and pore sizes, varying degrees of hydrophobicity, and differing abilities to separate acidic and/or basic components.
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Sponsored Products
Phenomenex
- HPLC
- Luna C18(2), Luna NH(2), Luna SCX, Luna Pheny-Hexyl, Luna PFP(2), Luna C8(2), Luna Silica(2), Luna CN, Luna HILIC
- Hydrophilic Interaction, Ion Exchange, Normal Phase, Reversed Phase, No Separation Mode
- 2.5, 3, 5, 10, 15 µm
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