| Description | This product GTVCR-WQ1499MR is an effective transcription system suitable for a variety of research, including the in vitro translation, self-amplifying mRNA studies and protein expression. The system was driven by the T7 promoter to efficiently generate mRNA with 30 nt poly(A) tail ecoding antibodyThis product GTVCR-WQ1499MR is an effective transcription system suitable for a variety of research, including the in vitro translation, self-amplifying mRNA studies and protein expression. The system was driven by the T7 promoter to efficiently generate mRNA with 30 nt poly(A) tail ecoding antibody which targeting IL1RL2. The vector contains the self-replicating Venezuelan equine encephalitis (VEE) virus RNA replicon, which resulting the mRNA expression at a high level.... Read More | The Creative Biolabs footprint-free human iPS (induced pluripotent stem) cell line carrying the APOE-ε2 variant was derived from Creative Biolabs' syngeneic iPSC line (catalog number NCL-2103-P91) through advanced genome editing tools. The results confirmed that iPS46 is a homozygous line with The Creative Biolabs footprint-free human iPS (induced pluripotent stem) cell line carrying the APOE-ε2 variant was derived from Creative Biolabs' syngeneic iPSC line (catalog number NCL-2103-P91) through advanced genome editing tools. The results confirmed that iPS46 is a homozygous line with stable homozygous transformation with Cys112 (TGC) from Arg112 (CGC) and Cys158 (TGC) from Arg158 (CGC) in APOE gene. The morphology of this human iPS cell line is similar to Human ES cells are the same. They also express pluripotency markers TRA-1-60, SSEA-3 and Oct4, and show strong endogenous alkaline phosphatase activity.
feature:
Derived from a single iPSC clone
Have the same genetic background
Ready-made-simply thaw the cells and inoculate them in a serum-free, feeder-free culture
No genetic modification and no virus
Shows the expression of pluripotency markers and endogenous alkaline phosphatase activity... Read More | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and further details.
The P301L mutation MAPT has been implicated in frontotemporal dementia and parkinsonism (Dumanchin et al., 1998). The mutation affects only the 4R isoforms of MAPT since the exon containing the mutation is spliced out of 3R isoforms (Hutton et al., 1998). Aggregated MAPT/tau protein in affected patients consisted mainly of the 4R isoform (Hutton et al., 1998). The P301L mutation promotes aggregation of MAPT/tau protein into ordered paired helical filaments and beta sheet formation in vitro (von Bergen et al., 2001).... Read More | Parabacteroides is a Gram-negative, anaerobic, non-spore-forming genus from the family Tannerellaceae. Currently, the genus Parabacteroides includes eight valid species with standing in nomenclature. The species Parabacteroides faecis and Parabacteroides johnsonii; faeces and Parabacteroides Parabacteroides is a Gram-negative, anaerobic, non-spore-forming genus from the family Tannerellaceae. Currently, the genus Parabacteroides includes eight valid species with standing in nomenclature. The species Parabacteroides faecis and Parabacteroides johnsonii; faeces and Parabacteroides gordonii; blood were all isolated for the first time in humans. Of all the species, Parabacteroides distasonis is the reference type strain for the genus Parabacteroides. To date, Parabacteroides distasonis has been shown to have beneficial effects on colorectal cancer. Multiple researchers have identified that levels of Parabacteroides distasonis in stool are inversely correlated to the presence of intestinal tumors. The evidence for the potential anti-inflammatory effects of Parabacteroides distasonis in colorectal cancer is further supported by the inverse correlation between Parabacteroides distasonis levels and IL-1β production in the gut, suggesting that Parabacteroides distasonis has anti-tumorigenic and anti-inflammatory potential in colorectal cancer patients. Further potential benefits of Parabacteroides distasonis have been identified, particularly in relation to obesity. In addition, several studies have suggested that Parabacteroides distasonis may play a role in various forms of autoimmunity.... Read More | Rhesus monkey is widely used in medical and biological research on human and animal related diseases even space travel due to its closeness to humans anatomically and physiologically. This product is collected from Rhesus monkey Veins or arteries tissue. The sample is negative for Herpes B Virus, Rhesus monkey is widely used in medical and biological research on human and animal related diseases even space travel due to its closeness to humans anatomically and physiologically. This product is collected from Rhesus monkey Veins or arteries tissue. The sample is negative for Herpes B Virus, retroviruses, SIV, SRV, & STLV. It can be applied for life science laboratory or biochemical experiment such as PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry.... Read More |