| Description | Lactobacillus species are normal flora of the human mouth, gastrointestinal tract, and female genital tract, where they produce lactic acid and competitively inhibit pathogenic organisms. Lactobacillus are small, slender, nonmotile, Gram-positive bacilli in chains. Immature colonies appear smooth, Lactobacillus species are normal flora of the human mouth, gastrointestinal tract, and female genital tract, where they produce lactic acid and competitively inhibit pathogenic organisms. Lactobacillus are small, slender, nonmotile, Gram-positive bacilli in chains. Immature colonies appear smooth, convex, and translucent. Some species of Lactobacillus used commonly as probiotics. They are most commonly used for diarrhea, including infectious diarrhea and diarrhea in people taking antibiotics. Some people also use lactobacillus for general digestion problems, irritable bowel syndrome; IBS, colic in infants, and many other conditions that involve the stomach and bowel.... Read More | Bacillus is a genus of Gram-positive, rod-shaped bacteria, a member of the phylum Bacillota. Bacillus species can be either obligate aerobes which are dependent on oxygen, or facultative anaerobes which can survive in the absence of oxygen. | Enterococcus are lactic acid bacteria; LAB comprising both pathogenic and commensal microorganisms ubiquitous in environment even as gut symbionts. They are extensively studied as potential candidate probiotics. Several number of Enterococcus strains have been reported to produce antimicrobial Enterococcus are lactic acid bacteria; LAB comprising both pathogenic and commensal microorganisms ubiquitous in environment even as gut symbionts. They are extensively studied as potential candidate probiotics. Several number of Enterococcus strains have been reported to produce antimicrobial compounds including bacteriocins. Bacteriocin production have be applied to preservation of a wide range of food products and is now being considered as a probiotic trait. Besides, bacteriocins are considered as promising alternative to fight emerging antimicrobial resistance. Enterococcus probiotics can be used in treatment and/or prevention of certain human and animal diseases such as alleviation of irritable bowel syndrome symptoms and antibiotic-induced diarrhea and prevention of different functional and chronic intestinal diseases. Moreover, some Enterococcus exhibit anticarcinogenic, hypocholesterolemic, as well as immune regulation effects.... Read More | iNeuMito™ biosensor is a mitochondrial calcium flux sensor. These cells are engineered to express iNeuMito™ biosensor, which has been developed to use a highly sensitive fluorescence-based biosensor as a reporter gene to monitor mitochondrial calcium flux and cytotoxicity. Excitation = iNeuMito™ biosensor is a mitochondrial calcium flux sensor. These cells are engineered to express iNeuMito™ biosensor, which has been developed to use a highly sensitive fluorescence-based biosensor as a reporter gene to monitor mitochondrial calcium flux and cytotoxicity. Excitation = 610nm; emission = 625nm. The iNeuMito™ biosensor is introduced into the cell using a proprietary magnetic liposome-mediated method and expressed in the mitochondria (using a marker protein such as COX IV).
iNeuATP™, a fluorescent biosensor, has also been custom incorporated into the human iNeuRapid™ cell line. With iNeuATP™, biosensor assays provide fast kinetics (resolution in seconds) when measuring real-time cellular ATP metabolism and cytotoxicity. The analysis of cellular oxidative phosphorylation directly reflects the health and function of mitochondria. Excitation = 535nm; emission = 550nm.
Starting Materials: immortalized human cell line.... Read More | The product SIRGT99541WQ-LNA is a type of small interfering RNA (siRNA) that targets A2m gene and regulates the expression of gene. The siRNA interferes with the expression of A2m gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA isThe product SIRGT99541WQ-LNA is a type of small interfering RNA (siRNA) that targets A2m gene and regulates the expression of gene. The siRNA interferes with the expression of A2m gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More |