| Description | Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from normal Cynomolgus monkey brain Vascular tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from normal Cynomolgus monkey brain Vascular tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays such as cell-cell interaction, adhesion, migration, PCR, Western blot, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry, or generating cell derivatives for desired research applications.... Read More | Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from Cynomolgus monkeys Brain Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assaysCynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from Cynomolgus monkeys Brain Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assays such as PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry.... Read More | iNeu™ human dopaminergic neurons are derived from human dermal cells using a non-integrated induced pluripotent stem cell (iPSC) line under fully defined proprietary induction and maturation conditions. iNeu™ cells are plated in a monolayer when cultured, are branched, and express iNeu™ human dopaminergic neurons are derived from human dermal cells using a non-integrated induced pluripotent stem cell (iPSC) line under fully defined proprietary induction and maturation conditions. iNeu™ cells are plated in a monolayer when cultured, are branched, and express biomarkers such as beta3-Tuj (neurons), tyrosine hydroxylase (TH) and dopamine transporter (DAT). iNeu™ can be used under mature conditions, co-culture conditions (used with astrocytes or other neuronal subtypes), and short-term functional characterization studies.... Read More | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and further details.
The P301L mutation MAPT has been implicated in frontotemporal dementia and parkinsonism (Dumanchin et al., 1998). The mutation affects only the 4R isoforms of MAPT since the exon containing the mutation is spliced out of 3R isoforms (Hutton et al., 1998). Aggregated MAPT/tau protein in affected patients consisted mainly of the 4R isoform (Hutton et al., 1998). The P301L mutation promotes aggregation of MAPT/tau protein into ordered paired helical filaments and beta sheet formation in vitro (von Bergen et al., 2001).... Read More | Marmoset monkeys are tree-dwelling small monkeys that habitat South American. This product is isolated from Marmosets Fallopian Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assays such as PCR, Western blot, Marmoset monkeys are tree-dwelling small monkeys that habitat South American. This product is isolated from Marmosets Fallopian Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assays such as PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry.... Read More |