| Description | The product SIRGT47166WQ-2F is a type of small interfering RNA (siRNA) that targets LIN28A gene and regulates the expression of gene. The siRNA interferes with the expression of LIN28A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The The product SIRGT47166WQ-2F is a type of small interfering RNA (siRNA) that targets LIN28A gene and regulates the expression of gene. The siRNA interferes with the expression of LIN28A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2_-deoxy-2_-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More | Anaerostipes is a Gram positive and anaerobic bacterial genus from the family of Lachnospiraceae. Anaerostipes occurs in the human gut. It may protect against colon cancer in humans by producing butyric acid. | iNeuMito™ biosensor is a mitochondrial calcium flux sensor. These cells are engineered to express iNeuMito™ biosensor, which has been developed to use a highly sensitive fluorescence-based biosensor as a reporter gene to monitor mitochondrial calcium flux and cytotoxicity. Excitation = iNeuMito™ biosensor is a mitochondrial calcium flux sensor. These cells are engineered to express iNeuMito™ biosensor, which has been developed to use a highly sensitive fluorescence-based biosensor as a reporter gene to monitor mitochondrial calcium flux and cytotoxicity. Excitation = 610nm; emission = 625nm. The iNeuMito™ biosensor is introduced into the cell using a proprietary magnetic liposome-mediated method and expressed in the mitochondria (using a marker protein such as COX IV).
iNeuATP™, a fluorescent biosensor, has also been custom incorporated into the human iNeuRapid™ cell line. With iNeuATP™, biosensor assays provide fast kinetics (resolution in seconds) when measuring real-time cellular ATP metabolism and cytotoxicity. The analysis of cellular oxidative phosphorylation directly reflects the health and function of mitochondria. Excitation = 535nm; emission = 550nm.
Starting Materials: immortalized human cell line.... Read More | This product GTVCR-WQ39MR is an effective transcription system suitable for a variety of research, including the in vitro translation, self-amplifying mRNA studies and protein expression. The system was driven by the T7 promoter to efficiently generate mRNA with 30 nt poly(A) tail ecoding antibody This product GTVCR-WQ39MR is an effective transcription system suitable for a variety of research, including the in vitro translation, self-amplifying mRNA studies and protein expression. The system was driven by the T7 promoter to efficiently generate mRNA with 30 nt poly(A) tail ecoding antibody which targeting VEGFA. The vector contains the self-replicating Venezuelan equine encephalitis (VEE) virus RNA replicon, which resulting the mRNA expression at a high level.... Read More | This product is a 33.5 kDa Human KIR2DS2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis. |