| Quantity | 20 nmol, 50 nmol, 100 nmol, 200 nmol | 5 slides | ~0.6x10^6 cells per 1ml of freezing medium (vial) | 1.5 million cells & Neural Plating-XF Medium | Inquire |
| Description | The product SIRGT00054WQ is a type of small interfering RNA (siRNA) that targets ACVR2A gene and regulates the expression of gene. The siRNA interferes with the expression of ACVR2A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has The product SIRGT00054WQ is a type of small interfering RNA (siRNA) that targets ACVR2A gene and regulates the expression of gene. The siRNA interferes with the expression of ACVR2A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More | Creative Biolabs' Alzheimer's Disease Brain Tissue Panel (TeHAD-Alz) is designed to rapidly screen brain tissue for Alzheimer's disease-specific genes or proteins. | iNeu™ human dopaminergic neurons are derived from human dermal cells using a non-integrated induced pluripotent stem cell (iPSC) line under fully defined proprietary induction and maturation conditions. iNeu™ cells are plated in a monolayer when cultured, are branched, and express iNeu™ human dopaminergic neurons are derived from human dermal cells using a non-integrated induced pluripotent stem cell (iPSC) line under fully defined proprietary induction and maturation conditions. iNeu™ cells are plated in a monolayer when cultured, are branched, and express biomarkers such as beta3-Tuj (neurons), tyrosine hydroxylase (TH) and dopamine transporter (DAT). iNeu™ can be used under mature conditions, co-culture conditions (used with astrocytes or other neuronal subtypes), and short-term functional characterization studies.... Read More | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in autosomal-dominant familial Parkinson's disease with late onset (Fonzo et al., 2006, Thaler et al., 2009). The G2019S mutation increases the kinase activity of LRRK2 causing increased autophosphorylation and substrate phosphorylation that may affect neuronal cell health in Parkinson's disease patients (West et al., 2005).... Read More | Streptococcus is a genus of Gram-positive coccus that belongs to the family Streptococcaceae, within the order Lactobacillales. Streptococcus thermophilus is a powerful probiotic strain that has well researched health benefits. This probiotic is often found in the colon and has many digestive, Streptococcus is a genus of Gram-positive coccus that belongs to the family Streptococcaceae, within the order Lactobacillales. Streptococcus thermophilus is a powerful probiotic strain that has well researched health benefits. This probiotic is often found in the colon and has many digestive, immunity and many other researched health benefits.... Read More |