| Description | Blautia is a genus of anaerobic bacteria with probiotic characteristics that occur widely in the feces and intestines of mammals. | The Creative Biolabs footprint-free human iPS (induced pluripotent stem) cell line carrying the APOE-ε2 variant was derived from Creative Biolabs' syngeneic iPSC line (catalog number NCL-2103-P91) through advanced genome editing tools. The results confirmed that iPS46 is a homozygous line with The Creative Biolabs footprint-free human iPS (induced pluripotent stem) cell line carrying the APOE-ε2 variant was derived from Creative Biolabs' syngeneic iPSC line (catalog number NCL-2103-P91) through advanced genome editing tools. The results confirmed that iPS46 is a homozygous line with stable homozygous transformation with Cys112 (TGC) from Arg112 (CGC) and Cys158 (TGC) from Arg158 (CGC) in APOE gene. The morphology of this human iPS cell line is similar to Human ES cells are the same. They also express pluripotency markers TRA-1-60, SSEA-3 and Oct4, and show strong endogenous alkaline phosphatase activity.
feature: Derived from a single iPSC clone Have the same genetic background Ready-made-simply thaw the cells and inoculate them in a serum-free, feeder-free culture No genetic modification and no virus Shows the expression of pluripotency markers and endogenous alkaline phosphatase activity... Read More | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in autosomal-dominant familial Parkinson's disease with late onset (Fonzo et al., 2006, Thaler et al., 2009). The G2019S mutation increases the kinase activity of LRRK2 causing increased autophosphorylation and substrate phosphorylation that may affect neuronal cell health in Parkinson's disease patients (West et al., 2005).... Read More | This product is a 58 kDa Human SPNS2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis. | Streptococcus is a genus of Gram-positive coccus that belongs to the family Streptococcaceae, within the order Lactobacillales. Streptococcus thermophilus is a powerful probiotic strain that has well researched health benefits. This probiotic is often found in the colon and has many digestive, Streptococcus is a genus of Gram-positive coccus that belongs to the family Streptococcaceae, within the order Lactobacillales. Streptococcus thermophilus is a powerful probiotic strain that has well researched health benefits. This probiotic is often found in the colon and has many digestive, immunity and many other researched health benefits.... Read More |