| Quantity | 20 nmol, 50 nmol, 100 nmol, 200 nmol | ~0.5x10^6 cells per 1ml of freezing medium (vial) | Inquire | Inquire | 20 nmol, 50 nmol, 100 nmol, 200 nmol |
| Description | The product SIRGT14048WQ-LNA is a type of small interfering RNA (siRNA) that targets HLA-F gene and regulates the expression of gene. The siRNA interferes with the expression of HLA-F gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The The product SIRGT14048WQ-LNA is a type of small interfering RNA (siRNA) that targets HLA-F gene and regulates the expression of gene. The siRNA interferes with the expression of HLA-F gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More | iNeuMito™ biosensor is a mitochondrial calcium flux sensor. These cells are engineered to express iNeuMito™ biosensor, which has been developed to use a highly sensitive fluorescence-based biosensor as a reporter gene to monitor mitochondrial calcium flux and cytotoxicity. Excitation = iNeuMito™ biosensor is a mitochondrial calcium flux sensor. These cells are engineered to express iNeuMito™ biosensor, which has been developed to use a highly sensitive fluorescence-based biosensor as a reporter gene to monitor mitochondrial calcium flux and cytotoxicity. Excitation = 610nm; emission = 625nm. The iNeuMito™ biosensor is introduced into the cell using a proprietary magnetic liposome-mediated method and expressed in the mitochondria (using a marker protein such as COX IV).
iNeuATP™, a fluorescent biosensor, has also been custom incorporated into the human iNeuRapid™ cell line. With iNeuATP™, biosensor assays provide fast kinetics (resolution in seconds) when measuring real-time cellular ATP metabolism and cytotoxicity. The analysis of cellular oxidative phosphorylation directly reflects the health and function of mitochondria. Excitation = 535nm; emission = 550nm.
Starting Materials: immortalized human cell line.... Read More | This product is a 10.4 kDa native human C5a protein isolated from normal human serum. It is availible for Functional Assays, ELISA, RIA. | Parasutterella is a genus of Gram-negative, circular/rod-shaped, obligate anaerobic, non-spore forming bacteria. In a study that examined the effect of introducing and reversing diet-induced obesity on the gut microbiome and metabolism in mice, Parasutterella was decreased in mice with diet-induced Parasutterella is a genus of Gram-negative, circular/rod-shaped, obligate anaerobic, non-spore forming bacteria. In a study that examined the effect of introducing and reversing diet-induced obesity on the gut microbiome and metabolism in mice, Parasutterella was decreased in mice with diet-induced obesity and increased in controls and reversal of the high fat diet with a healthier alternative (normal chow). Other studies have shown increases of Parasutterella with sugar and alcohol consumption.... Read More | The product SIRGT95889WQ is a type of small interfering RNA (siRNA) that targets Ear4 gene and regulates the expression of gene. The siRNA interferes with the expression of Ear4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has The product SIRGT95889WQ is a type of small interfering RNA (siRNA) that targets Ear4 gene and regulates the expression of gene. The siRNA interferes with the expression of Ear4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More |