| Description | Akkermansia is a genus in the phylum Verrucomicrobia; Bacteria with the type species Akkermansia muciniphila. Among the next-generation beneficial microbes that have been identified, Akkermansia muciniphila is a promising candidate. Akkermansia muciniphila is a strict anaerobe recently isolated fromAkkermansia is a genus in the phylum Verrucomicrobia; Bacteria with the type species Akkermansia muciniphila. Among the next-generation beneficial microbes that have been identified, Akkermansia muciniphila is a promising candidate. Akkermansia muciniphila is a strict anaerobe recently isolated from human faeces and uses the mucin as thesole sources of carbon and nitrogen elements. Due to this unique function and its high universality and richness in almost all life stages, Akkermansia muciniphila opened new avenues for the application in next-generation therapeutic probiotic. It is a bacterium of oval shape, non-motile and Gram-negative andforms no endospores and widely distributed in the intestines of human and animals. Akkermansia muciniphila is one of the normal gutsymbionts throughout our life. Currently, a large number of researches on Akkermansia muciniphila mainly focused on explaining its relationship with diseases. It promises to be a therapeutic target in the microbiota-related diseases, such as colitis, metabolic syndrome, immune diseases and cancer. Preliminary human datasuggest oral administration of Akkermansia muciniphila safe, butits effect needs to be further verified in more human clinical trials in the near future.... Read More | Enterococcus are lactic acid bacteria; LAB comprising both pathogenic and commensal microorganisms ubiquitous in environment even as gut symbionts. They are extensively studied as potential candidate probiotics. Several number of Enterococcus strains have been reported to produce antimicrobial Enterococcus are lactic acid bacteria; LAB comprising both pathogenic and commensal microorganisms ubiquitous in environment even as gut symbionts. They are extensively studied as potential candidate probiotics. Several number of Enterococcus strains have been reported to produce antimicrobial compounds including bacteriocins. Bacteriocin production have be applied to preservation of a wide range of food products and is now being considered as a probiotic trait. Besides, bacteriocins are considered as promising alternative to fight emerging antimicrobial resistance. Enterococcus probiotics can be used in treatment and/or prevention of certain human and animal diseases such as alleviation of irritable bowel syndrome symptoms and antibiotic-induced diarrhea and prevention of different functional and chronic intestinal diseases. Moreover, some Enterococcus exhibit anticarcinogenic, hypocholesterolemic, as well as immune regulation effects.... Read More | iNeu™ human dopaminergic neurons are derived from human dermal cells using a non-integrated induced pluripotent stem cell (iPSC) line under fully defined proprietary induction and maturation conditions. iNeu™ cells are plated in a monolayer when cultured, are branched, and express iNeu™ human dopaminergic neurons are derived from human dermal cells using a non-integrated induced pluripotent stem cell (iPSC) line under fully defined proprietary induction and maturation conditions. iNeu™ cells are plated in a monolayer when cultured, are branched, and express biomarkers such as beta3-Tuj (neurons), tyrosine hydroxylase (TH) and dopamine transporter (DAT). iNeu™ can be used under mature conditions, co-culture conditions (used with astrocytes or other neuronal subtypes), and short-term functional characterization studies.... Read More | This product is a 213 kDa recombinant human CD35 protein with a C-terminal 10-His tag expressed in the mouse myeloma cell line, NS0. It is available for Binding Activity Assays. | The product SIRGT63524WQ-2MOE is a type of small interfering RNA (siRNA) that targets PIKFYVE gene and regulates the expression of gene. The siRNA interferes with the expression of PIKFYVE gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. TheThe product SIRGT63524WQ-2MOE is a type of small interfering RNA (siRNA) that targets PIKFYVE gene and regulates the expression of gene. The siRNA interferes with the expression of PIKFYVE gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More |