| Description | The product SIRGT27964WQ-2F is a type of small interfering RNA (siRNA) that targets NRXN3 gene and regulates the expression of gene. The siRNA interferes with the expression of NRXN3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNAThe product SIRGT27964WQ-2F is a type of small interfering RNA (siRNA) that targets NRXN3 gene and regulates the expression of gene. The siRNA interferes with the expression of NRXN3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2_-deoxy-2_-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More | Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. BacteroidesBacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 1% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.... Read More | The Creative Biolabs footprint-free human iPS (induced pluripotent stem) cell line carrying the APOE-ε2 variant was derived from Creative Biolabs' syngeneic iPSC line (catalog number NCL-2103-P91) through advanced genome editing tools. The results confirmed that iPS46 is a homozygous line with The Creative Biolabs footprint-free human iPS (induced pluripotent stem) cell line carrying the APOE-ε2 variant was derived from Creative Biolabs' syngeneic iPSC line (catalog number NCL-2103-P91) through advanced genome editing tools. The results confirmed that iPS46 is a homozygous line with stable homozygous transformation with Cys112 (TGC) from Arg112 (CGC) and Cys158 (TGC) from Arg158 (CGC) in APOE gene. The morphology of this human iPS cell line is similar to Human ES cells are the same. They also express pluripotency markers TRA-1-60, SSEA-3 and Oct4, and show strong endogenous alkaline phosphatase activity.
feature:
Derived from a single iPSC clone
Have the same genetic background
Ready-made-simply thaw the cells and inoculate them in a serum-free, feeder-free culture
No genetic modification and no virus
Shows the expression of pluripotency markers and endogenous alkaline phosphatase activity... Read More | Lactobacillus species are normal flora of the human mouth, gastrointestinal tract, and female genital tract, where they produce lactic acid and competitively inhibit pathogenic organisms. Lactobacillus are small, slender, nonmotile, Gram-positive bacilli in chains. Immature colonies appear smooth, Lactobacillus species are normal flora of the human mouth, gastrointestinal tract, and female genital tract, where they produce lactic acid and competitively inhibit pathogenic organisms. Lactobacillus are small, slender, nonmotile, Gram-positive bacilli in chains. Immature colonies appear smooth, convex, and translucent. Some species of Lactobacillus used commonly as probiotics. They are most commonly used for diarrhea, including infectious diarrhea and diarrhea in people taking antibiotics. Some people also use lactobacillus for general digestion problems, irritable bowel syndrome; IBS, colic in infants, and many other conditions that involve the stomach and bowel.... Read More | This product is a 43.2 kDa Human GRPR membrane protein expressed in in vitro wheat germ expression system with proprietary liposome technology. The protein is for research use only and is not approved for use in humans or in clinical diagnosis. |