| Description | The product SIRGT72532WQ-2F is a type of small interfering RNA (siRNA) that targets MYDGF gene and regulates the expression of gene. The siRNA interferes with the expression of MYDGF gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNAThe product SIRGT72532WQ-2F is a type of small interfering RNA (siRNA) that targets MYDGF gene and regulates the expression of gene. The siRNA interferes with the expression of MYDGF gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2_-deoxy-2_-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More | iNeu™ human keratinocytes are derived from human dermal fibroblasts, using a feeder-free, serum-free, genetic-free, virus-free induced pluripotent stem cell (iPSC) line, and have fully defined proprietary induction and maturation conditions. iNeu™ cells can be cultured in a monolayer andiNeu™ human keratinocytes are derived from human dermal fibroblasts, using a feeder-free, serum-free, genetic-free, virus-free induced pluripotent stem cell (iPSC) line, and have fully defined proprietary induction and maturation conditions. iNeu™ cells can be cultured in a monolayer and can express different biomarkers, such as Cytokeratin-18. iNeu™ can be used under mature conditions, co-culture conditions (used with fibroblasts, melanocytes or other epidermal subtypes), and short-term functional characterization studies.... Read More | Recombinant Norovirus GI.1 Virus-like Particles (NoV GI.1 VLPs) are produced in Baculovirus/Insect cell expression system, assembled with VP1 structure protein. VLP is mimicking the native 3D structure of viruses which can elicit strong immune responses. However, VLPs lack viral genomic material Recombinant Norovirus GI.1 Virus-like Particles (NoV GI.1 VLPs) are produced in Baculovirus/Insect cell expression system, assembled with VP1 structure protein. VLP is mimicking the native 3D structure of viruses which can elicit strong immune responses. However, VLPs lack viral genomic material which makes them non-infectious, unable to replicate and enhance the safety during manufacture and administration. NoV GI.1 VLPs can be used in the development of NoV GI.1 diagnostics and in vaccine development and R&D (including use as an immunogen).... Read More | Parabacteroides is a Gram-negative, anaerobic, non-spore-forming genus from the family Tannerellaceae. Currently, the genus Parabacteroides includes eight valid species with standing in nomenclature. The species Parabacteroides faecis and Parabacteroides johnsonii; faeces and Parabacteroides Parabacteroides is a Gram-negative, anaerobic, non-spore-forming genus from the family Tannerellaceae. Currently, the genus Parabacteroides includes eight valid species with standing in nomenclature. The species Parabacteroides faecis and Parabacteroides johnsonii; faeces and Parabacteroides gordonii; blood were all isolated for the first time in humans. Of all the species, Parabacteroides distasonis is the reference type strain for the genus Parabacteroides. To date, Parabacteroides distasonis has been shown to have beneficial effects on colorectal cancer. Multiple researchers have identified that levels of Parabacteroides distasonis in stool are inversely correlated to the presence of intestinal tumors. The evidence for the potential anti-inflammatory effects of Parabacteroides distasonis in colorectal cancer is further supported by the inverse correlation between Parabacteroides distasonis levels and IL-1β production in the gut, suggesting that Parabacteroides distasonis has anti-tumorigenic and anti-inflammatory potential in colorectal cancer patients. Further potential benefits of Parabacteroides distasonis have been identified, particularly in relation to obesity. In addition, several studies have suggested that Parabacteroides distasonis may play a role in various forms of autoimmunity.... Read More | Creative Biolabs' Neuropathy Frozen Tissue Panels are designed for the study of Alzheimer's disease, Parkinson's disease, dementia, multiple sclerosis, progressive supranuclear palsy (PSP) and depression. |