| Description | The product SIRGT50806WQ is a type of small interfering RNA (siRNA) that targets CDPF1 gene and regulates the expression of gene. The siRNA interferes with the expression of CDPF1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA isThe product SIRGT50806WQ is a type of small interfering RNA (siRNA) that targets CDPF1 gene and regulates the expression of gene. The siRNA interferes with the expression of CDPF1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More | Bifidobacterium are Gram-positive, heterofermentative, anaerobic bacteria with a distinctive bifid; i.e. Y shape after which they are named. They wre originally isolated from the faeces of breast-fed infants, members of the genus Bifidobacterium are commonly found in the GI tract of mammals. In Bifidobacterium are Gram-positive, heterofermentative, anaerobic bacteria with a distinctive bifid; i.e. Y shape after which they are named. They wre originally isolated from the faeces of breast-fed infants, members of the genus Bifidobacterium are commonly found in the GI tract of mammals. In humans, Bifidobacterium resides within the GI tract, from birth to old age. Disturbances in the microbiota are linked to an ever-growing number of immune-linked disease states including IBD, atopic allergy, arthritis, and obesity. Therefore, there is a significant interest in treating these diseases through microbial or "probiotic" supplementation of patients, including Bifidobacterium. Data from mouse models and clinical trials indicate that Bifidobacterium may have beneficial effects for treating and preventing immune-linked diseases, including gut-associated and systemic conditions. Bifidobacterium have been commercially exploited as probiotic agents due to their associated health benefits and GRAS.... Read More | Creative Biolabs' frozen tissue slides are ideal for rapid identification of the cellular localization of RNA or proteins. Additional organs are available upon request. | iNeu™ human dopaminergic neurons are derived from human dermal cells using a non-integrated induced pluripotent stem cell (iPSC) line under fully defined proprietary induction and maturation conditions. iNeu™ cells are plated in a monolayer when cultured, are branched, and express iNeu™ human dopaminergic neurons are derived from human dermal cells using a non-integrated induced pluripotent stem cell (iPSC) line under fully defined proprietary induction and maturation conditions. iNeu™ cells are plated in a monolayer when cultured, are branched, and express biomarkers such as beta3-Tuj (neurons), tyrosine hydroxylase (TH) and dopamine transporter (DAT). iNeu™ can be used under mature conditions, co-culture conditions (used with astrocytes or other neuronal subtypes), and short-term functional characterization studies.... Read More | Creative Biolabs offers a range of recombinant cell lines for Immunotherapy discovery and development. |