| Description | Creative Biolabs offers the overexpression cell line which expressing the co-inhibitory and co-stimulatory immune checkpoints of human, mouse and cynomolgus monkey origin to accelerate immunotherapy discovery and development. | Bifidobacterium are Gram-positive, heterofermentative, anaerobic bacteria with a distinctive bifid; i.e. Y shape after which they are named. They wre originally isolated from the faeces of breast-fed infants, members of the genus Bifidobacterium are commonly found in the GI tract of mammals. In Bifidobacterium are Gram-positive, heterofermentative, anaerobic bacteria with a distinctive bifid; i.e. Y shape after which they are named. They wre originally isolated from the faeces of breast-fed infants, members of the genus Bifidobacterium are commonly found in the GI tract of mammals. In humans, Bifidobacterium resides within the GI tract, from birth to old age. Disturbances in the microbiota are linked to an ever-growing number of immune-linked disease states including IBD, atopic allergy, arthritis, and obesity. Therefore, there is a significant interest in treating these diseases through microbial or "probiotic" supplementation of patients, including Bifidobacterium. Data from mouse models and clinical trials indicate that Bifidobacterium may have beneficial effects for treating and preventing immune-linked diseases, including gut-associated and systemic conditions. Bifidobacterium have been commercially exploited as probiotic agents due to their associated health benefits and GRAS.... Read More | The Creative Biolabs footprint-free human iPS (induced pluripotent stem) cell line carrying the APOE-ε2 variant was derived from Creative Biolabs' syngeneic iPSC line (catalog number NCL-2103-P91) through advanced genome editing tools. The results confirmed that iPS46 is a homozygous line with The Creative Biolabs footprint-free human iPS (induced pluripotent stem) cell line carrying the APOE-ε2 variant was derived from Creative Biolabs' syngeneic iPSC line (catalog number NCL-2103-P91) through advanced genome editing tools. The results confirmed that iPS46 is a homozygous line with stable homozygous transformation with Cys112 (TGC) from Arg112 (CGC) and Cys158 (TGC) from Arg158 (CGC) in APOE gene. The morphology of this human iPS cell line is similar to Human ES cells are the same. They also express pluripotency markers TRA-1-60, SSEA-3 and Oct4, and show strong endogenous alkaline phosphatase activity.
feature:
Derived from a single iPSC clone
Have the same genetic background
Ready-made-simply thaw the cells and inoculate them in a serum-free, feeder-free culture
No genetic modification and no virus
Shows the expression of pluripotency markers and endogenous alkaline phosphatase activity... Read More | This product GTTS-WQ7127MR is a type of mRNA having 120 nt poly(A) tail and modified with Cap 0 & N1-Methylpseudo-UTP. It ecodes the monoclonal antibody that targets LHCGR gene. The antibody can be applied in Controlled Ovarian Stimulation (COS) research. | The product SIRGT02109WQ-2F is a type of small interfering RNA (siRNA) that targets AP2A1 gene and regulates the expression of gene. The siRNA interferes with the expression of AP2A1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNAThe product SIRGT02109WQ-2F is a type of small interfering RNA (siRNA) that targets AP2A1 gene and regulates the expression of gene. The siRNA interferes with the expression of AP2A1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2_-deoxy-2_-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More |