| Description | The product SIRGT04230WQ-LNA is a type of small interfering RNA (siRNA) that targets APOC3 gene and regulates the expression of gene. The siRNA interferes with the expression of APOC3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The The product SIRGT04230WQ-LNA is a type of small interfering RNA (siRNA) that targets APOC3 gene and regulates the expression of gene. The siRNA interferes with the expression of APOC3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More | Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from normal Cynomolgus monkey vena cava tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from normal Cynomolgus monkey vena cava tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays such as cell-cell interaction, adhesion, migration, PCR, Western blot, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry, or generating cell derivatives for desired research applications.... Read More | iNeuMito™ biosensor is a mitochondrial calcium flux sensor. These cells are engineered to express iNeuMito™ biosensor, which has been developed to use a highly sensitive fluorescence-based biosensor as a reporter gene to monitor mitochondrial calcium flux and cytotoxicity. Excitation = iNeuMito™ biosensor is a mitochondrial calcium flux sensor. These cells are engineered to express iNeuMito™ biosensor, which has been developed to use a highly sensitive fluorescence-based biosensor as a reporter gene to monitor mitochondrial calcium flux and cytotoxicity. Excitation = 610nm; emission = 625nm. The iNeuMito™ biosensor is introduced into the cell using a proprietary magnetic liposome-mediated method and expressed in the mitochondria (using a marker protein such as COX IV).
iNeuATP™, a fluorescent biosensor, has also been custom incorporated into the human iNeuRapid™ cell line. With iNeuATP™, biosensor assays provide fast kinetics (resolution in seconds) when measuring real-time cellular ATP metabolism and cytotoxicity. The analysis of cellular oxidative phosphorylation directly reflects the health and function of mitochondria. Excitation = 535nm; emission = 550nm.
Starting Materials: immortalized human cell line.... Read More | This product is a Mouse Gm11437 membrane protein expressed in vitro E.coli expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis. | Rhesus monkey is widely used in medical and biological research on human and animal related diseases even space travel due to its closeness to humans anatomically and physiologically. This product is isolated from tissue of Rhesus monkey. Cells are negative for bacteria, yeast, fungi, mycoplasma, Rhesus monkey is widely used in medical and biological research on human and animal related diseases even space travel due to its closeness to humans anatomically and physiologically. This product is isolated from tissue of Rhesus monkey. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays such as cell-cell interaction, adhesion, migration, PCR, Western blot, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry, or generating cell derivatives for desired research applications.... Read More |