Maldi TOF Mass Spectrometer (MALDI TOF MS)

MALDI TOF mass spectrometers (matrix-assisted laser desorption/ionization/time-of-flight) are amongst the most popular mass spec instruments in biology. They combine two technologies, the “soft” MALDI ionization source and the TOF mass analyzer. The latter measures an ion’s mass-to-charge ratio (m/z) by measuring the time it takes to reach a detector. The former volatilizes and ionizes those molecules using a laser, a target, and an organic compound called a matrix. In MALDI, a sample (for instance, a collection of tryptic peptides) is mixed with matrix, spotted and dried (crystallized) on the surface of a metal target plate. Upon irradiation with laser light, the matrix absorbs the energy and converts it to heat, which then causes the sample to ionize and explode off the plate into the mass analyzer. MALDI TOF mass spectrometers come in two basic flavors, MALDI TOF MS and MALDI TOF/TOF MS; the latter enables tandem MS (MS/MS) studies.
CompanyShimadzuShimadzuShimadzuShimadzuShimadzu
ItemiMScope QT Imaging Mass MicroscopeAxima Assurance MALDI Time of Flight Mass SpectrometerAxima Confidence MALDI TOF Mass SpectrometerAXIMA-iD Plus Microorganism AnalysisMegaTOF Megadalton MALDI Mass Spectrometer
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Figures
Catalog NumberiMScope QTAXIMA AssuranceAxima ConfidenceAXIMA-iD PlusMegaTOF
Price
Ionization Method(s)Atmospheric Pressure MALDI (AP-MALDI)MALDIMALDIMALDIMALDI
Mass AnalyzerQ-TOFTOFTOFMALDI-TOF MSTOF
ResolutionInquire>5000 FWHM5000 FWHM in linear mode; 15000 FWHM in reflectron modeInquire180 to 200 kDa
Scanning SpeedInquireInquireInquireInquire15 sec/position
Mass RangeInquire1 kDa to 500 kDa1 kDa to 500 kDaVaries based on MALDI-TOF system used0.01 to 1.5 Mda
DescriptionInquire

An affordable, robust option for laboratories requiring routine manual or automated analysis of a wide variety of sample classes, the AXIMA Assurance provides high-quality, rapid MALDI mass spectra and an array of software tools for data processing and reporting. Incorporating a variable repetition

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An affordable, robust option for routine sample analysis performed manually or automatically, the AXIMA Confidence offers reliable mass information and MS/MS-derived structural detail. A linear mode enables outstanding levels of analysis of high-molecular weight samples while the reflectron mode,

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Certain microorganisms can cause severe diseases and considerable damage, and need to be identified quickly and reliably. The easy-to-use AXIMA-iDPlus Microbial Identification System is the ideal tool to address these concerns. With AXIMA-iDPlus, cultured microorganisms can be directly applied to ... Read MoreThe MegaTOF has been developed by optimizing the integration of a high-performance Shimadzu linear MALDI TOF mass spectrometer with a CovalX high-mass system, allowing outstanding detection of macromolecules up to 1,500 kDa.

Features
  • Ultrahigh sensitivity
  • Detects macromolecules up to 1,500,000 Da
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