A triple-quadrupole mass spectrometer, also known as QqQ, is a tandem MS method in which the first and third quadrupoles act as mass filters and the second causes fragmentation of the analyte through interaction with a collision gas—it is a radiofrequency-only quadrupole, and can be used in either SIM or scan mode. The method can be used to obtain structural information or for quantitation. For structural mass spec, a common sequence is product ion scan, precursor ion scan, and neutral loss scan, followed by selected reaction monitoring (SRM) or multiple reaction monitoring (MRM).
Increased selectivity, improved S/N, lower limits of quantitation, wider linear range, and improved accuracy are some of the benefits of this technique, which encompasses triple-quad LC-MS, GC-MS, GC-MSD, and ICP-MS. Although QqQ is a particularly useful method for all stages of pharmaceutical development, it is a reliable option for many applications, such as clinical research, food safety, forensics, environmental, and proteomics.
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| Company | Thermo Fisher Scientific | Thermo Fisher Scientific | Thermo Fisher Scientific | Thermo Fisher Scientific |
| Item | TSQ Altis™ MD Mass Spectrometer | Thermo Scientific™ TSQ Altis™ Plus Triple Quadrupole Mass Spectrometer | Thermo Scientific™ TSQ Quantis™ Plus Triple Quadrupole Mass Spectrometer | TSQ Quantis™ MD Mass Spectrometer |
| Catalog Number | IQLAAEGAAXFAQSMBLC | IQLAAEGAAXFAQSMBMI | IQLAAEGAAXFAQTMBMJ | IQLAAEGAAXFAQTMBLA |
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| Description | Achieve the sensitivity to perform routine quantitative analyses with remarkable speed and robustness. The Thermo Scientific™ TSQ Quantis™ MD Series mass spectrometer can be used by clinical diagnostic laboratories to meet their routine requirements for laboratory developed tests (LDTs). With ActiveAchieve the sensitivity to perform routine quantitative analyses with remarkable speed and robustness. The Thermo Scientific™ TSQ Quantis™ MD Series mass spectrometer can be used by clinical diagnostic laboratories to meet their routine requirements for laboratory developed tests (LDTs). With Active Ion Management (AIM+) technology,the TSQ Quantis MD Series delivers confident quantitation for routine analyses of human specimens.... Read More | Ultimate quantitative performance made possible
Overcome the most demanding quantitative workflow challenges. With superior acquisition speeds, enhanced sensitivity, prototypical selectivity, and exceptional robustness, the TSQ Altis Plus mass spectrometer delivers unprecedented accuracy and Ultimate quantitative performance made possible
Overcome the most demanding quantitative workflow challenges. With superior acquisition speeds, enhanced sensitivity, prototypical selectivity, and exceptional robustness, the TSQ Altis Plus mass spectrometer delivers unprecedented accuracy and precision for low-level compound detection and quantitation in complex matrices that redefines ultimate instrument performance.... Read More | Extended quantitative performance made accessible
Experience reliability and sensitivity, and report results with confidence. The Thermo Scientific TSQ Quantis Plus mass spectrometer provides effortless method set up with industry-leading multi-channel solutions and automated reporting that enable Extended quantitative performance made accessible
Experience reliability and sensitivity, and report results with confidence. The Thermo Scientific TSQ Quantis Plus mass spectrometer provides effortless method set up with industry-leading multi-channel solutions and automated reporting that enable robust high-throughput quantitation.... Read More | Develop in vitro diagnostic tests for demanding quantitative analyses leveraging the enhanced sensitivity and remarkable speed and robustness of the Thermo Scientific™ TSQ Altis™ MD Series Mass Spectrometer. The TSQ Altis MD Series mass spectrometer, a Class I medical device, offers superb Develop in vitro diagnostic tests for demanding quantitative analyses leveraging the enhanced sensitivity and remarkable speed and robustness of the Thermo Scientific™ TSQ Altis™ MD Series Mass Spectrometer. The TSQ Altis MD Series mass spectrometer, a Class I medical device, offers superb analytical performance and features the maximum usability, sensitivity and robustness required for laboratory developed tests (LDTs) from clinical diagnostic laboratories. With superb analytical performance, this platform features maximum usability, sensitivity, and robustness.... Read More |
| Mass Analyzer | Triple quadrupole | Inquire | Inquire | Triple quadrupole |
| Mass Range | 5 to 3000 m/z | Inquire | Inquire | 5 to 3000 m/z |
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