Triple Quadrupole Mass Spectrometer (QqQ MS)

A triple-quadrupole mass spectrometer, also known as QqQ, is a tandem MS method in which the first and third quadrupoles act as mass filters and the second causes fragmentation of the analyte through interaction with a collision gas—it is a radiofrequency-only quadrupole, and can be used in either SIM or scan mode. The method can be used to obtain structural information or for quantitation. For structural mass spec, a common sequence is product ion scan, precursor ion scan, and neutral loss scan, followed by selected reaction monitoring (SRM) or multiple reaction monitoring (MRM). Increased selectivity, improved S/N, lower limits of quantitation, wider linear range, and improved accuracy are some of the benefits of this technique, which encompasses triple-quad LC-MS, GC-MS, GC-MSD, and ICP-MS. Although QqQ is a particularly useful method for all stages of pharmaceutical development, it is a reliable option for many applications, such as clinical research, food safety, forensics, environmental, and proteomics.

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CompanyShimadzuShimadzuShimadzuShimadzu
ItemLCMS-8050RX Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-8045RX Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-8060RX Triple Quadrupole LC/MS/MS Mass SpectrometerLCMS-8065XE Triple Quadrupole LC/MS/MS Mass Spectrometer
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Catalog NumberLCMS-8050RXLCMS-8045RXLCMS-8060RXLCMS-8065XE
Price
DescriptionIncorporating Shimadzu’s proprietary ultrafast technologies (UF Technologies), the triple quadrupole LCMS-8050RX offers outstanding measurement speeds and quantitative performance.
Specific and highly sensitive Multiple Reaction Monitoring (MRM) multi-component analysis is improved with a heated
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The workhorse triple quad LCMS-8045RX is ideal for routine analysis, delivering a balance of robustness, sensitivity and cost-effectiveness, making it the perfect option for production laboratories.
The heated ESI probe promotes the ionization of wide range of targeted compounds, while the
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The triple quad LCMS-8060RX utilizes proprietary technologies and more efficient ion transfer to achieve outstanding speed and sensitivity.
A heat-assisted electrospray ionization probe delivers a highly efficient desolvation process that promotes the ionization of a wide range of target compounds
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The LCMS-8065XE introduces innovative technologies that deliver exceptional performance with evolved, efficient and exact capabilities.
The instrument incorporates Shimadzu’s complete Ultra Fast Mass Spectrometry (UFMS) technology suite:
  • World-class 5 msec positive/negative ion switching with
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Ionization Method(s)ESI, APCI, Dual Ionization, Micro-ESIESI, APCI, Dual Ionization, Micro-ESIESI, APCI, Dual Ionization, Micro-ESIESI, APCI (optional)
Mass AnalyzerQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rodsQ1 & Q3 are molybdenum hyperbolic mass filters with pre-rods; Q1 includes post-rods
Mass Range2 to 2000 m/zInquirem/z 2 to 2,000m/z 2 to 2,00
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