Gas Chromatograph Mass Spectrometer / GC MS Instrument

Gas chromatograph mass spectrometers (GC MS) are to volatile chemical compounds what liquid chromatography (LC) MS systems are to materials in solution: they separate and analyze gas-phase molecules.

How do GC MS Instruments work?
In LC, compounds are fractionated based on their differential affinity for the separation’s mobile (liquid) and stationary phases (column packing material). In GC, heated, volatile compounds are injected into a flowing gas stream and separated as that stream flows through a long hollow tube (sometimes tens of meters in length) coated with a stationary phase material. In GC MS chromatography, the fractionated compounds are then ionized (typically by electron ionization) and injected into the mass spec analyzer, most commonly a single quadrupole (though triple quadrupoles and time-of-flight analyzers are also available).

What are GC MS Instruments Used For?
Gas chromatograph mass spectrometers are generally used to analyze small, relatively non-polar compounds, and are widely used in forensics, food safety, environmental monitoring, and petrochemicals, among others.

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CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemDFS™ Magnetic Sector GC-HRMSISQ 7610 Single Quadrupole GC-MSOrbitrap Exploris™ GC 240 Mass SpectrometerOrbitrap Exploris™ GC Mass SpectrometerTSQ 9610 Triple Quadrupole GC-MS/MS
Catalog NumberIQLAAEGAALFABKMAEGIQLAAAGABPFARJMBLYIQLAAAGABPFARJMBLX
Price
Temperature RangeInquireUp to 350 °C (ion source); up to 400 °C (transfer line)InquireInquireUp to 400 °C (filament replaceable at temperature)
Resolution> 60,000 RUnit mass resolution; automatic tuning down to 0.4 uUp to 240,000 at m/z 200Up to 30,000 at m/z 200Selectable SRM: 0.7 u, 1.5 u, 2.5 u, or custom 0.7-1.5 u
Ionization Method(s)Full range of Ionization Modes Available: EI, CI, and FD/FIEI, CIEI/PCI/NCIInquireEI, AEI, CI (PCI and NCI)
Mass AnalyzerUltra-high precision toroidal electrostatic analyzer and magnetic analyzerSingle QuadrupoleHigh-field Orbitrap mass analyzerInquireTriple Quadrupole
Scanning Speed0.1 to 10,000 Da/sec.Up to 20,000 u/sUp to 40 Hz at resolution setting 7,500 at m/z 200Up to 40 Hz at resolution setting 7,500 at m/z 200Up to 20,000 u/s
Mass Range2 to 6000 m/z1.2-1,100 um/z 30 to 3,000m/z 30 to 3,0001.2-1,100 u
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