Gas Chromatograph Mass Spectrometer / GC MS Instrument

Gas chromatograph mass spectrometers (GC MS) are to volatile chemical compounds what liquid chromatography (LC) MS systems are to materials in solution: they separate and analyze gas-phase molecules.

How do GC MS Instruments work?
In LC, compounds are fractionated based on their differential affinity for the separation’s mobile (liquid) and stationary phases (column packing material). In GC, heated, volatile compounds are injected into a flowing gas stream and separated as that stream flows through a long hollow tube (sometimes tens of meters in length) coated with a stationary phase material. In GC MS chromatography, the fractionated compounds are then ionized (typically by electron ionization) and injected into the mass spec analyzer, most commonly a single quadrupole (though triple quadrupoles and time-of-flight analyzers are also available).

What are GC MS Instruments Used For?
Gas chromatograph mass spectrometers are generally used to analyze small, relatively non-polar compounds, and are widely used in forensics, food safety, environmental monitoring, and petrochemicals, among others.

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CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemTSQ 9610 Triple Quadrupole GC-MS/MSDFS™ Magnetic Sector GC-HRMSISQ 7610 Single Quadrupole GC-MSOrbitrap Exploris™ GC 240 Mass SpectrometerOrbitrap Exploris™ GC Mass Spectrometer
Catalog NumberIQLAAEGAALFABKMAEGIQLAAAGABPFARJMBLYIQLAAAGABPFARJMBLX
Price
Temperature RangeUp to 400 °C (filament replaceable at temperature)InquireUp to 350 °C (ion source); up to 400 °C (transfer line)InquireInquire
ResolutionSelectable SRM: 0.7 u, 1.5 u, 2.5 u, or custom 0.7-1.5 u> 60,000 RUnit mass resolution; automatic tuning down to 0.4 uUp to 240,000 at m/z 200Up to 30,000 at m/z 200
Ionization Method(s)EI, AEI, CI (PCI and NCI)Full range of Ionization Modes Available: EI, CI, and FD/FIEI, CIEI/PCI/NCIInquire
Mass AnalyzerTriple QuadrupoleUltra-high precision toroidal electrostatic analyzer and magnetic analyzerSingle QuadrupoleHigh-field Orbitrap mass analyzerInquire
Scanning SpeedUp to 20,000 u/s0.1 to 10,000 Da/sec.Up to 20,000 u/sUp to 40 Hz at resolution setting 7,500 at m/z 200Up to 40 Hz at resolution setting 7,500 at m/z 200
Mass Range1.2-1,100 u2 to 6000 m/z1.2-1,100 um/z 30 to 3,000m/z 30 to 3,000
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