LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemOrbitrap Fusion™ Lumos™ Tribrid™ Mass SpectrometerOrbitrap Eclipse™ Tribrid™ Mass SpectrometerOrbitrap Exploris™ 240 Mass SpectrometerOrbitrap IQ-X™ Tribrid™ Mass SpectrometerQ Exactive™ UHMR Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
Citations
Catalog NumberIQLAAEGAAPFADBMBHQIQLAAEGAAPFADBMBKSIQLAAEGAAPFARBMBKPIQLAAEGAAPFADBMBMAIQLAAEGAAPFALGMAZR
Price
Ionization Method(s)HESIInquireESI and HRAMESIInquire
Mass AnalyzerOrbitrapOrbitrapOrbitrapOrbitrapUHMR Hybrid Quadrupole-Orbitrap™
Scanning SpeedInquireOTMSn up to 40 Hz ITMSn up to 45 HzUp to 22 Hz at resolution setting of 15,000 at m/z 200Inquireup to 12 Hz at resolution setting of 12,500 at m/z 400
Resolution7500-500,000 (FWHM) at m/z 2007500 to 500,000 (FWHM) at m/z 200Up to 240,000 at m/z 2007500 to 500,000 (FWHM) at m/z 200200,000 at m/z 400
DescriptionExcel at the most challenging of applications, including low level PTM analysis, multiplexed relative quantitation using isobaric tags, intact protein characterization, as well as MSn analysis of small molecules with the new Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer. This... Read MoreOne system, maximum insights
Today’s cutting-edge research pushes LC-MS to its limits. Obtaining high confidence insights to enable accurate resolution of subtle differences and avoid costly dead-ends is needed faster than ever before. The Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer
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The Thermo Scientific Orbitrap Exploris 240 mass spectrometer combines application flexibility with the performance to drive discovery and identification, plus receive the quantitative precision and accuracy you need to confidently scale up and achieve impact. With operational simplicity through ... Read MoreBuilt for small-molecule analyses, the Thermo Scientific™ Orbitrap IQ-X™ Tribrid™ mass spectrometer reveals your most complex chemical structures? with ultimate confidence, ease, and experimental versatility.The Thermo Scientific™ Q Exactive™ UHMR Hybrid Quadrupole-Orbitrap™ mass spectrometer is the first to provide the unique combination of unprecedented ultra-high mass range resolution, highest sensitivity, and MS2 and pseudo-MS3 capabilities needed to go beyond what’s possible with today’s native MS ... Read More
QuantityEAEAEAEAEA
TypeInquireInquireOrbitrap LC-MSOrbitrap Tribrid Mass SpectrometerQuadrupole-Orbitrap LC-MS
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