LC MS Instrument

Comprising two components, a liquid-phase separation system and a mass spectrometer, liquid chromatograph mass spectrometers (LC MS instruments) couple sample fractionation and analysis. The separation can be accomplished via standard liquid chromatography, HPLC, UPLC, or even nano-LC. Any liquid-phase separation will do, so long as its output can be directed into the mass analyzer (for instance, via an electrospray ionization source). The mass spectrometer is similarly flexible, ranging from the simplest single quadrupole to a Fourier transform ion cyclotron resonance instrument. Just remember, in a liquid chromatograph mass spectrometer the column flow is continuous, meaning the mass analyzer must be fast enough to thoroughly analyze one peak before the next one comes off the column. And, unlike with MALDI MS, once a peak is analyzed, it’s gone.
CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemOrbitrap Eclipse™ Tribrid™ Mass SpectrometerOrbitrap Exploris™ 120 Mass SpectrometerOrbitrap Fusion™ Lumos™ Tribrid™ Mass SpectrometerThermo Scientific™ Tox Explorer™ Collection for Orbitrap™ Exploris™ 120 MSTox Explorer™ Collection for Quantis™ Plus MS
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Catalog NumberIQLAAEGAAPFADBMBKSIQLAAEGAAPFARBMBKQIQLAAEGAAPFADBMBHQWFLOW-62002WFLOW-62003
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Ionization Method(s)InquireESI and HRAMHESIInquireInquire
Mass AnalyzerOrbitrapOrbitrapOrbitrapInquireInquire
Scanning SpeedOTMSn up to 40 Hz ITMSn up to 45 HzUp to 22 Hz at resolution setting of 15,000 at m/z 200InquireUp to 22 HzInquire
Resolution7500 to 500,000 (FWHM) at m/z 200Up to 120,000 at m/z 2007500-500,000 (FWHM) at m/z 200Up to 120,000 (FWHM) at m/z 200, demonstrates outstanding resolving power, according to a product pageInquire
DescriptionOne system, maximum insights
Today’s cutting-edge research pushes LC-MS to its limits. Obtaining high confidence insights to enable accurate resolution of subtle differences and avoid costly dead-ends is needed faster than ever before. The Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer
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The Thermo Scientific Orbitrap Exploris 120 mass spectrometer accelerates your route to qualitative and quantitative confidence for both method development and everyday testing purposes. With its unique ability to provide consistently accurate data and a design made for operational simplicity, it ... Read MoreExcel at the most challenging of applications, including low level PTM analysis, multiplexed relative quantitation using isobaric tags, intact protein characterization, as well as MSn analysis of small molecules with the new Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer. This... Read MoreAn all-in-one LC-MS/MS workflow solution for toxicology. HRAM option includes experimentally obtained compound database and HRAM spectral library with retention times of over 1800 compoundsAn all-in-one LC-MS/MS workflow solution for toxicology. Increase productivity with SRM acquisition speeds enabling faster polarity switching of both positive and negative compounds. Triple quadrupole option includes experimentally obtained compound database and retention times of over 1100 ... Read More
QuantityEAEAEAEAEA
TypeInquireOrbitrap LC-MSInquireTox Explorer CollectionTox Explorer Collection
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